Schwannoma maligno dos seios paranasais

Pádua, Sharlene Castanheira; Soares, Vítor Yamashiro Rocha; Queiroz, Andre; Nakanishi, Márcio; Nascimento, Luiz Augusto

doi:10.1590/s1808-86942012000400026

Cited by 6 publications

(4 citation statements)

References 7 publications

(33 reference statements)

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“…Malignant neurilemmoma in the nasal cavity and paranasal sinuses is extremely rare. 6,7 The ethmoid and maxillary…”

Section: Discussionmentioning

confidence: 99%

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Neurilemmoma of the Nasal Cavity and Paranasal Sinuses

Wang

2021

Ear Nose Throat J

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Objectives: Neurilemmoma in the nasal cavity and paranasal sinuses is very rare. The study aimed to improve the understanding of neurilemmoma in the nasal cavity and paranasal sinuses. Materials and Methods: The clinical data of 10 patients with neurilemmoma in the nasal cavity and paranasal sinuses treated from January 2014 to June 2019 in our hospital were retrospectively studied. Results: There were 6 females and 4 males patients in our study. The mean age was 49.5 years (range 37-77 years), and the most common clinical symptom was unilateral nasal obstruction. The site of tumor included the nasal cavity, maxillary sinus, ethmoid sinus, and sphenoid sinus. There were 2 cases with malignant neurilemmoma. Nine patients underwent functional endoscopic sinus surgery (FESS); however, 1 patient underwent FESS combined with the lateral rhinotomy for complete resection of the tumor. Two patients with malignant neurilemmoma received postoperative radiotherapy. The mean follow-up was 3.82 years (range 2-7 years). There were no incidences of tumor recurrence during the study period. Conclusions: Neurilemmoma in the nasal cavity and paranasal sinuses is a mainly benign tumor. Complete surgical excision by FESS is the only treatment option for neurilemmoma in the nasal cavity and paranasal sinuses; while malignant neurilemmoma needs postoperative radiotherapy.

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“…Malignant neurilemmoma in the nasal cavity and paranasal sinuses is extremely rare. 6,7 The ethmoid and maxillary…”

Section: Discussionmentioning

confidence: 99%

“…Malignant neurilemmoma in the nasal cavity and paranasal sinuses is extremely rare. 6,7 The ethmoid and maxillary sinuses most often occur, and the nasal fossa and sphenoid sinus come next. 8…”

Section: Discussionmentioning

confidence: 99%

Neurilemmoma of the Nasal Cavity and Paranasal Sinuses

Wang

2021

Ear Nose Throat J

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“…A presença de achados de morfologia neural contribui grandemente para a hipótese. A negatividade do marcador HMB-45 também corrobora o diagnóstico do schwanomas, tal como ocorreu no presente caso relatado, e a positividade da proteína S100 confirma o diagnóstico 13 .…”

Section: Discussionunclassified

Schwanoma Maligno de Nervo Periférico Metastático para Pulmão e Glândula Adrenal: Relato de Caso

Lucca¹,

Antunes²,

Maffini³

et al. 2021

Rev. Bras. Cancerol.

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Introdução: O schwanoma e um tumor pouco frequente que se origina das células de Schwann que recobrem os prolongamentos nervosos. A malignidade desses tumores e ainda mais rara, correspondendo a 5-10% de todos os sarcomas. O prognostico e reservado, mesmo após completa ressecção cirúrgica. Relato do caso: Paciente do sexo masculino, 79 anos, apresentou-se com lesão crostosa em perna esquerda com dois meses de evolução. A biopsia da lesão inicialmente revelou sarcoma pleomórfico, mas seu padrão imuno-histoquímico confirmou tumor maligno da bainha do nervo periférico. O tumor desenvolveu metástase linfonodal, pulmonar e adrenal dentro de poucos anos após o diagnostico inicial. A ressecção do tumor adrenal não foi possível. O paciente desenvolveu síndrome paraneoplásica e teve piora do estado clinico, evoluindo a óbito. Conclusão: Tendo em vista a forma inespecífica do aparecimento do tumor e sua agressividade, e importante ressaltar o papel da ressecção cirúrgica ampla no seu tratamento. Além disso, fica evidente a necessidade de novos relatos desse tipo de neoplasia para melhor definição de uma conduta mais apropriada, principalmente em casos de recorrência ou disseminação metastática.

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“…Schwannomas rarely metastasize to regional lymph nodes, and distant metastases are infrequent [23]. The literature has reported that distant metastases might involve the lungs, and they are associated with intracranial invasion [24]. …”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Sinonasal Tract and the Pterygopalatine Fossa with or without Intracranial Extension

Zhou¹,

Xing

Gao³

et al. 2015

ORL

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Aims: Compared with those in other head and neck regions, schwannomas in the nasal cavity or paranasal sinuses are rare. The aim of this study was to present the experience of the authors in 11 schwannoma cases of the sinonasal tract and pterygopalatine fossa over a decade. Methods: A retrospective study from 2003 to 2014. Results: Three female and 8 male patients from 22 to 61 years of age (mean age 42 years) were admitted. The most common complaints were unilateral nasal congestion. A total of 10 of the patients received surgery, including 6 functional endoscopic sinus surgeries (FESS). The postoperative course was generally uneventful. Among the patients, 10 remained regionally asymptomatic, and there has been no clinical or radiological evidence of recurrence or residual tumor. Conclusion: Surgical treatment is effective for schwannomas of the sinonasal tract and the pterygopalatine fossa with a low recurrence rate. Conducting CT and MRI (particularly fluid-attenuated inversion recovery) before surgery is mandatory. FESS could become the primary treatment of choice.

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Schwannoma maligno dos seios paranasais

Cited by 6 publications

References 7 publications

Neurilemmoma of the Nasal Cavity and Paranasal Sinuses

Neurilemmoma of the Nasal Cavity and Paranasal Sinuses

Schwanoma Maligno de Nervo Periférico Metastático para Pulmão e Glândula Adrenal: Relato de Caso

Schwannoma of the Sinonasal Tract and the Pterygopalatine Fossa with or without Intracranial Extension

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