Rabdomiossarcoma de cabeça e pescoço: 24 casos e revisão da literatura

Abstract

Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissues, more common in childhood, mainly located in the head and neck. It presents varied clinical and biological behavior and requires individualized management. Aim To describe information on patients with head and neck RMS diagnosed and treated in a hospital, and to compare them to results in the literature. Study design: Descriptive and retrospective. Materials and Methods A retrospective analysis of data from 24 patients with head and neck rhabdomyosarcoma diagnosed and treated in a hospital from 1994 to 2008. Results The mean age was 7.79 years. According to gender, 54.17 % were males and 45.83 % were female. All patients underwent chemotherapy (CT), 62.5% of them also underwent radiotherapy (RT) and 16.67% were submitted to surgery. Of the 24 patients, 8 (33.3%) died, 6 (25%) were found free of neoplasia and 2 (8.3%) experienced tumor recurrence. Conclusion The RMS of the head and neck often presents with nonspecific symptoms. Individualized multimodal therapy should be performed for these patients, including surgery, chemotherapy and radiotherapy.

Congenital Rhabdomyosarcoma Presenting as a Neck Mass at Birth

“…Other possible locations include the genitourinary tract, limbs, thorax, and retroperitoneum. The majority of cases are sporadic; however, some may be associated with genetic syndromes [3, 4]. …”

Total laryngectomy in neonate with laryngeal sarcoma: perioperative management: Case report

“…The distribution of the age of presentation is bimodal: the first peak is between the ages of 2 and 6 years and the second peak between the ages of 10 and 18 years. Among them, the incidence of laryngeal sarcoma is less than 0.1% [16], [17].…”

Rabdomiossarcoma Mamário Bilateral Em Adolescente: Um Relato De Caso

“…Do ponto de vista histológico, o rabdomiossarcoma está subdividido em tipo histológico embrionário, alveolar e pleomórfico (HAYS et al, 1997). Os principais subtipos de rabdomiossarcoma da infância são o embrionário e o alveolar (DE MATTOS et al, 2014), sendo o embrionário o subtipo mais comum, com aproximadamente 60% dos casos, e o subtipo alveolar o segundo mais comum, atingindo aproximadamente 20% dos casos (MORETTI et al, 2010). O embrionário ocorre principalmente em crianças com idade inferior a 10 anos, em sítios de cabeça e pescoço, trato geniturinário e retroperitônio.…”

“…O local mais comum de apresentação é a região da cabeça e pescoço, seguida pelo trato geniturinário, extremidades, tórax e retroperitônio (MORETTI et al, 2010), podendo invadir outros tecidos através de metástases em gânglios linfáticos regionais, pulmões, medula, ossos, fígado, nódulos subcutâneos, cérebro (FERMAN, 2005). A topografia mamária como manifestação inicial desses tumores é extremamente rara (TAMIOLAKIS et al, 2004).…”