Avaliação endoscópica nasal de crianças e adolescentes com fibrose cística

Franco, Letícia Paiva; Camargos, Paulo Augusto Moreira; Becker, Helena Maria Gonçalves; Guimarães, Roberto Eustáquio Santos

doi:10.1590/s1808-86942009000600006

Cited by 9 publications

(7 citation statements)

References 46 publications

(75 reference statements)

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“…In this study, there was no statistically significant association between nasal polyps and patients' age; however, 64.3% of patients with polyps in this study by Franco et al [22] were between four and 12 years of age, which coincides with ages in the report by Sakano and colleagues [20] (88.89% of cases of polyposis in patients under 15 years of age). That is, among Brazilian children with CF, the prevalence of polyps in younger children is quite high.…”

Section: Endoscopic Findingssupporting

confidence: 64%

“…Only two patients complained of anosmia and about 10% complained of periorbital or facial pain [22]. It is important to highlight that, although some studies show that up to 100% of patients demonstrate pansinusitis on tomography of the paranasal sinuses, 20% of these patients did not present any of the symptoms listed, and 36% did not present bilateral changes in the middle meatus [22]. One possible explanation for a low frequency of chronic sinonasal complains would be a matter of priority, being pulmonary and gastrointestinal problems prioritized by patients and family.…”

Section: Symptomatologymentioning

confidence: 99%

“…Franco and colleagues [22] found nasal polyps in only 14% of children and adolescents with CF even using an evaluative technique similar to that used in other studies published recently. Weber and Ferrari [26] found nasal polyps in 39.1% of 23 CF patients aged one year and nine months to 22 years and 8 months.…”

Section: Endoscopic Findingsmentioning

confidence: 99%

“…Among 100 CF children and adolescents studied by Franco and coworkers [22], patients with nasal polyps had associated nasal secretions, identified using endoscopy, but endoscopy did not identify the presence of nasal polyps and symptoms such as cough, rhinorrhea, oral breathing, restless sleep, headache, and nasal obstruction. In this study, there was no statistically significant association between nasal polyps and patients' age; however, 64.3% of patients with polyps in this study by Franco et al [22] were between four and 12 years of age, which coincides with ages in the report by Sakano and colleagues [20] (88.89% of cases of polyposis in patients under 15 years of age).…”

Section: Endoscopic Findingsmentioning

confidence: 99%

“…That is, among Brazilian children with CF, the prevalence of polyps in younger children is quite high. Nasal polyps have been identified in a child as young as 8 months old; a differential diagnosis was made using computed tomography of the nose and paranasal sinuses [22]. …”

Section: Endoscopic Findingsmentioning

confidence: 99%

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Cystic Fibrosis: Brazilian ENT Experience

Sih

Godinho

Franco

et al. 2012

International Journal of Otolaryngology

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Most published studies about Cystic Fibrosis (CF) are European or North American. There are still few publications about the characteristics of fibrocystic populations in developing countries. The incidence of cystic fibrosis (CF) in Brazil varies among different regions (1 : 10,000 in Minas Gerais, 1 : 9,500 in Paraná, 1 : 8,700 in Santa Catarina, and 1 : 1600 in Rio Grande do Sul). The prevalence of the DF508 mutation also varies according to population: 33% in Sao Paulo, 49% in Rio Grande do Sul, 27% in Santa Catarina, and 52% in Minas Gerais. Cough and nasal obstruction are the most common symptoms. The variation in nasal polyposis prevalence may be explained by population genotypic characteristics in a country that spans a continent. Findings on nasal endoscopy and computed tomography (CT) have better correlation than do this information compared with surgical and clinical history. Microbiologic studies suggest a high level of early contamination of the airways. Sensorineural hearing loss (SNHL) occurs in these patients as a result of ototoxic antibiotics. The data compiled in this paper is useful, but also lead to the general agreement that more research would be welcome due to the unique characteristics of this country.

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Section: Endoscopic Findingssupporting

confidence: 64%

Section: Symptomatologymentioning

confidence: 99%

Section: Endoscopic Findingsmentioning

confidence: 99%

Section: Endoscopic Findingsmentioning

confidence: 99%

Section: Endoscopic Findingsmentioning

confidence: 99%

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Cystic Fibrosis: Brazilian ENT Experience

Sih

Godinho

Franco

et al. 2012

International Journal of Otolaryngology

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Sleep in children with cystic fibrosis: More under the covers

Reiter

Breuer

Cohen‐Cymberknoh

et al. 2021

Pediatric Pulmonology

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Cystic fibrosis (CF) is a chronic multisystem disease with manifestations from birth. It involves the entire respiratory system, with increased cough, and recurrent pulmonary infections, and it also leads to intestinal malabsorption, all of which can have an impact on sleep. In this review, we summarize the available literature on the various sleep disturbances in children with CF. Sleep quality and sleep efficiency are often impaired in children with CF. They may be accompanied by symptoms associated with sleep‐disordered breathing (SDB), and objective findings, such as nocturnal hypoxemia. Importantly, a strong association has been shown between SDB and the severity of lung disease, and some studies have reported a similar association for sleep quality. Further research is needed to better characterize the association of sleep disturbances with respiratory outcomes and the impact of treatment of sleep disorders on pulmonary status in children with CF.

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