Clinical and cytogenetic aspects of giant cell tumor of the sternum

Engel, Edgard Eduard; Nogueira-Barbosa, Marcello Henrique; Yamashita, Mauricio Eiji de Almeida Santos; Cipriano, Federico Enrique Garcia; Valera, Elvis Terci; Brassesco, María Sol

doi:10.1590/s1807-59322011000800034

Cited by 3 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 3 , 6 Cases of lung metastasis 1 to 10 years after tumor removal have been described. 3 , 7 Rarely, less than 2% of malignant GCT, defined as a sarcoma, arise synchronously with GCT, or at the site of a previously resected GCT. 8 …”

Section: Discussionmentioning

confidence: 99%

“…Only 16 cases with a morphologically confirmed diagnosis have been described in the literature ( Table 1 ). 6 , 7 , 11 – 22…”

Section: Discussionmentioning

confidence: 99%

“…The extent of resection depends on the tumor location, and subtotal sternectomy is the most common procedure. 6 , 7 , 11 , 13 , 17 , 21 Futani et al 14 reported extended curettage of the tumor followed by filling of the defect with polymethyl methacrylate (PMMA) with no recurrence observed 7 years after surgery. Similarly, Segawa et al 19 completed the chest wall reconstruction after curettage and cement usage with polypropylene mesh and a titanium mesh plate.…”

Section: Discussionmentioning

confidence: 99%

“… 6 , 11 , 12 , 17 , 21 Some authors used different types of mesh or a polyester patch for the same purpose. 6 , 11 , 21 Engel et al 7 reported on the use of a biomaterial mesh only reconstruction without any respiratory complications. Faria et al 13 reported successful chest wall reconstruction with fascia lata after GCT resection.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Surgical management of rare benign tumors of the sternum

Gritsiuta

Bracken

Downs

et al. 2021

MOJCR

View full text Add to dashboard Cite

Primary benign tumors of the sternum are an exceedingly rare entity. Surgical techniques regarding intervention for these lesions are not clearly defined in the literature given their scarcity. Operative techniques include en-bloc resection of the tumor, and this has proven to be successful in preventing local recurrence despite benign nature of the lesion. Given the often extensive defect created by the excision, reconstruction is frequently necessary; depending on the size of the defect, either autologous bone grafting or the use of synthetic materials may be indicated. This study serves to present two cases of rare primary benign tumors of the sternum, giant cell tumors and osteoma spongiosum and to summarize the available literature. We present a review of the literature of 17sternal giant cell tumor cases reported so far including our patient and unique case of osteoma spongiosum of the sternum, that discusses their surgical management, as well as reconstructive techniques that provided an excellent clinical result and a lack of recurrence on long term follow-up.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Only 16 cases with a morphologically confirmed diagnosis have been described in the literature ( Table 1 ). 6 , 7 , 11 – 22…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Surgical management of rare benign tumors of the sternum

Gritsiuta

Bracken

Downs

et al. 2021

MOJCR

View full text Add to dashboard Cite

show abstract

“…The malignant nature of the tumor and the need to sacrifice bilateral sternoclavicular joints posed a challenge to surgery and reconstruction. Engel et al 10 performed a subtotal sternectomy with the division of bilateral sternoclavicular joints and disarticulation of the bodymanubrium joint. Rigid reconstruction was done using mesh, and soft tissue coverage was done using bilateral pectoral advancement flaps.…”

Section: Discussionmentioning

confidence: 99%

Primary malignant giant cell tumor of the sternum

et al. 2021

View full text Add to dashboard Cite

Primary malignant giant cell tumor (PMGCT) is a diagnosis based on the presence of a high-grade sarcomatous component along with a typical benign giant cell tumor (GCT). We report the first case of PMGCT of the sternum in a 28-year-old male with painless swelling over the manubrium sterni. The differential diagnoses of PMGCT and giant cell-rich osteosarcoma were considered. Surgical resection was performed, and the reconstruction was done with a neosternum using polymethyl methacrylate and prolene mesh. At 30 months follow-up, the patient is disease-free.

show abstract