Relationship of Bode Index to Functional Tests in Chronic Obstructive Pulmonary Disease

Abstract

OBJECTIVETo determine if there is a correlation between the BODE Index and variables assessed during the Activities of Daily Living assessment, performance on lower limber tests, and peripheral muscle impairment of the upper limb in patients with chronic obstructive pulmonary disease.MATERIALS AND METHODSTen men (aged 58 to 80 years old) with moderate to very severe obstruction were evaluated and classified by the BODE Index. They were evaluated by pulmonary ventilation (V̇E), oxygen consumption (V̇O2), and carbonic gas production (V̇CO2) on the ADL assessment; Distance Walking (DW) in the Six Minute Walking Test (6MWT) and the Six Minute Walking Test on Treadmill (6MWTT); number of repetitions in the Sit-to-Stand Test; and the Hand Grip Strength Test. Correlations were evaluated between the classification and the tests performed (Pearson and Spearman test, p<0.05).RESULTSThe mean of the total score for the BODE Index was 2.80 (±1.03), with three patients scoring in the first quartile (Q1) and seven scoring in the second quartile (Q2). This Index showed a negative correlation with the 6MWTT (r=−0.86), the Sit-to-Stand Test (r=−0.66), and the Hand Grip Strength Test (r=−0.83).CONCLUSIONSOur results show that there is no correlation between the BODE Index and the ventilatory and metabolic responses in the Activities of Daily Living assessment. On the other hand, a correlation was observed between the BODE Index and the variables assessed in the 6MWTT, Sit-to-Stand Test, and Hand Grip Strength Test in moderate to very severe Chronic Obstructive Pulmonary Disease patients. This suggests that these tests can be employed as predictors of physical exercise capacity, perhaps as complementary tests to the BODE Index.

COPD patients' oxygen uptake and heart rate on-kinetics at cycle-ergometer: correlation with their predictors of severity

“…Furthermore, it reflects upper-limb peripheral muscle weakness evaluated by the manual dynamometer 37 and exercise capacity assessed by the 2-minute Sit-to-Stand Test test and the 6MWT on a treadmill 37 , measures that may also reflect the level of limitation of the physical activities of daily life according to the time spent per day in various activities and body positions, including walking, standing, and the intensity of movement measured when the patient is walking 38 . Additionally, there are moderate correlations between FEV 1 and distance traveled at 6MWT with VO 2 on-kinetics, unlike the results of the study by Borghi-Silva et al 16 , in which only correlations with the 6MWT were found.…”

Neuromuscular electrical stimulation improves exercise tolerance in chronic obstructive pulmonary disease patients with better preserved fat-free mass

“…In this context, several authors have found substantial alterations in muscle structure,2 bioenergetics,3 nutritional status, 4 BODE index5 and function,6 especially but not exclusively in the appendicular muscles of the lower limbs 7. …”

Prognostic value of the six-minute walk test in end-stage renal disease life expectancy: a prospective cohort study

“…In addition, the six-minute walk test (6MWT) has proved to be an excellent tool for functional capacity evaluation and has been widely used in patients with chronic diseases (5-9). This method has demonstrated prognostic value in pulmonary hypertension patients (10) and has been considered to be a predictor of mortality in patients with heart failure (HF) (6,11).…”