Correlation Between the Water Drinking Test and Modified Diurnal Tension Curve in Untreated Glaucomatous Eyes

Vasconcelos-Moraes, C. G.; Susanna, Remo

doi:10.1590/s1807-59322008000400004

Cited by 51 publications

(56 citation statements)

References 19 publications

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“…Correlation between peak IOP measured after WDT and 24-hour peak IOP has been reported. 6 In our patients, abnormal IOP peaks were detected after provocative testing using water ingestion during …”

Section: Intraocular Pressure Managementmentioning

confidence: 50%

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Continuous Intraocular Pressure Monitoring by Means of the Sensimed Triggerfish® System

Vetrugno¹,

Apruzzese²,

Lindell³

et al. 2011

European Ophthalmic Review

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Glaucoma is a progressive, chronic and irreversible neuropathy with typical structural changes at the optic nerve head and with functional defects in the visual field, leading to blindness at the end stage. It is estimated that over 60 million people worldwide are now affected by this disease and this number will dramatically increase to about 80 million by 2020. Glaucoma is the second leading cause of blindness in the world: it is estimated that 10% of people affected by glaucoma progress to blindness. 1Glaucoma is a multifactorial disease, but the only proven way to reduce its progression is by lowering intraocular pressure (IOP), by means of pharmacological, laser or surgical therapy. Intraocular Pressure ManagementIOP is a biological parameter that has a 24-hour biorhythm: in the majority of people it shows little variation -without clinically significant differences during the 24-hour period -while in some cases, IOP may be higher during the morning, or in the afternoon, or during the night. Triggerfish ® is a system enabling continuous IOP monitoring based on a disposable contact lens with a sensor linked to a telemetric microprocessor. The purpose of this project was to investigate the clinical applicability of the system as an additional tool, providing useful information for the management of glaucoma patients. Of eight evaluated patients, two cases are presented in detail in this report. The monitoring system that provides 24-hour continuous data appears to be very promising, as it captures clinically useful, real-life IOP fluctuations day and night while patients maintain normal activities, including undisturbed sleep.

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Section: Intraocular Pressure Managementmentioning

confidence: 50%

“…2 4 Both the ibopamine test and WDT were shown to correlate with daytime peak IOP. 5,6 A relationship between WDT and 24-hour peak IOP has been suggested. 7 Finally a 24-hour tonometric curve with IOP measurements taken also during the night may be established.…”

Section: Intraocular Pressure Managementmentioning

confidence: 99%

Continuous Intraocular Pressure Monitoring by Means of the Sensimed Triggerfish® System

Vetrugno¹,

Apruzzese²,

Lindell³

et al. 2011

European Ophthalmic Review

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show abstract

“…The results of the WDT have been shown to correlate well with intraocular pressure (IOP) peaks occurring during daytime (13) . A correlation between WDT results and progression of glaucoma has also been demonstrated (14,15) .…”

Section: Resumo Objetivo: Avaliar a Espessura De Coroide (Ec) E Sua Vmentioning

confidence: 96%

Choroidal thickness variation in highly myopic eyes during the water drinking test

Germano¹,

Hatanaka²,

Susanna³

2016

Arquivos Brasileiros De Oftalmologia

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Purpose: To evaluate variations in choroidal thickness (CT) during the water drinking test (WDT) in emmetropic eyes (EE) and highly myopic eyes (ME) using spectral-domain optical coherence tomography (SD-OCT). Methods: Clinical trial performed at a tertiary care hospital comprising 30 randomly selected eyes. The WDT and SD-OCT macular scans were performed 10 and 45 min after water ingestion in 15 myopic and 15 EE of 15 healthy patients in each group. Primary study outcomes were average macular CT measured by SD-OCT and intraocular pressure (IOP) during the WDT. Results: The mean spherical equivalent refraction was 0.15 ± 0.24 D in emmetropic and -7.1 ± 1.75 D in ME (p<0.001). No statistical differences between EE and ME were observed during the WDT response. EE had higher CT compared with ME at the fovea (361.4 ± 55.4 vs 257.9 ± 95.3; p<0.001), 3 mm nasal to the fovea (158.0 ± 71.8 vs 122.5 ± 54.5; p=0.047), and 3 mm temporally to the fovea (310.6 ± 52.4 vs 247.6 ± 90.1; p=0.05). Regarding CT variation, significant differences in foveal CT at 10 min after water ingestion were observed in both EE and ME, with no statistically significant difference observed between groups. A moderate correlation between IOP peak during the WDT and CT was demonstrated in ME (r=0.52; p=0.04). Conclusions:No statistically significant differences in CT variation during the WDT were observed between EE and ME, indicating similar behavior of the choroidal bed during the WDT in both groups. Further, CT was thinner in highly ME, with CT variation unable to explain elevations in IOP observed during the WDT.

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“…Çalışma, Helsinki Deklarasyonu'nda kabul edilen prensiplere uygun bir şekilde yürütülmüş olup, dâhil edilen tüm katılım-cılara çalışma hakkında ayrıntılı bilgi verilerek aydınlatılmış onam formu imzalatıldı. 19,20 Su tüketimi (hidrasyon), aynı zamanda episkleral venöz basınç artışına ve buna ikincil santral ve periferal venöz basınç artışına yol açar ve bu durum geçici negatif aköz dışa akımla sonuçlanır. Dışa akım yeteneğinin azalması sonucu GİB yüksekliği meydana gelir.…”

Section: Gereç Ve Yöntemlerunclassified

The Effect of Water Drinking Test on the Corneal Biomechanical Properties and Central Corneal Thickness in Patients with Glaucoma Suspect

Kaya¹,

Dönmez²,

Arıkan³

et al. 2016

Turkiye Klinikleri J Ophthalmol

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lokom hastalığı, progresif bir optik nöropatidir ve uygun tedavi edilmediğinde geri dönüşümsüz görme kaybına neden olur.1 Bilinen en önemli risk faktörü yüksek göz içi basıncı (GİB) olmakla birlikte, Turkiye Klinikleri J Ophthalmol 2016;25(4) 225 Glokom Şüphesi Olan Hastalarda Su İçme Testinin Korneanın Biyomekanik Özellikleri ve Santral Kornea Kalınlığı Üzerine Etkisi Ö ÖZ ZE ET T A Am ma aç ç: : Bu çalışmada, glokom şüphesi olan hastalarda su içme testinin korneanın biyomekanik özellikleri ve santral kornea kalınlığı üzerine etkisinin değerlendirilmesi amaçlanmıştır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Glokom şüphesi olan 31 hastanın 31 gözü çalışmaya alındı. Goldmann aplanasyon tonometresi ile göz içi basıncı (GİB) ve ultrasonik pakimetri ile santral kornea kalınlıklarının (SKK) bazal ölçümleri yapıldı. Oküler Cevap Analizörü ile korneal kompanse göz içi basıncı (GİBkk), Goldmann ile uyumlu göz içi basıncı (GİBg), korneal direnç faktörü (KDF) ve korneal histerezis (KH) değerleri ölçüldü. Tüm ölçümler her hasta için başlangıçta ve 5 dk içinde 1 L su içmelerinin ardından 15 dk'lık aralarla üç defa uygulandı. B Bu ul lg gu ul la ar r: : Çalışma populasyonunun ortalama yaşı 57,9±7,4 (aralık, 43-67) yıldı. Hastaların GİBkk, GİBg ve KH ölçümlerinde, su içme testinin 15, 30 ve 45. dakikalarında bazal ölçümlere göre istatistiksel olarak anlamlı artış saptandı (p<0,001). Hastaların KDF ölçümlerinde, su içme testinden sonra bazal değere göre 15, 30 ve 45. dakikalarda anlamlı düşme saptandı (p=0,022). Su içme testinden sonra SKK ölçümlerinde istatistiksel anlamlı değişiklik saptanmadı (p=0,466). S So on nu uç ç: : Glokom şüphesi olan hastalarda su yükleme testi GİB değerlerinde anlamlı artışa ve kornea biyomekanik özelliklerinde değişikliğe neden olmaktadır. Ancak, testin santral kornea kalınlığı üzerine herhangi bir etkisi olmamaktadır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Göz hipertansiyonu; kornea A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : It is aimed to evaluate the influence of water drinking test (WDT) on corneal biomechanical factors and central corneal thickness (CCT) in patients with glaucoma suspect. M Ma at te e--r ri ia al l a an nd d M Me et th ho od ds s: : Thirty-one eyes of 31 patients with suspected glaucoma were enrolled in this study. Baseline evaluation of intraocular pressure with Goldmann applanation tonometer (GAT) and CCT with ultrasonic pachymeter were performed. Corneal-compensated intraocular pressure (IOPcc), Goldmann-correlated IOP (IOPg), corneal hysteresis (CH), and corneal resistance factor (CRF) were measured by ocular response analyzer (ORA). Such measurements were performed at baseline and 3 times with 15 minutes intervals after drinking 1 liter of water in 5 minutes for each participants. R Re e--s su ul lt ts s: : The mean age of study population was 57.9±7.4 (range, 43-67 years) years. A statistically significant increase in IOPcc, IOPg and CH was found at 15, 30 and 45 minutes of WDT when compared to baseline scores (p<0.001). I...

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Correlation Between the Water Drinking Test and Modified Diurnal Tension Curve in Untreated Glaucomatous Eyes

Cited by 51 publications

References 19 publications

Continuous Intraocular Pressure Monitoring by Means of the Sensimed Triggerfish® System

Continuous Intraocular Pressure Monitoring by Means of the Sensimed Triggerfish® System

Choroidal thickness variation in highly myopic eyes during the water drinking test

The Effect of Water Drinking Test on the Corneal Biomechanical Properties and Central Corneal Thickness in Patients with Glaucoma Suspect

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