Association between self-reported oral health, tooth loss and atherosclerotic burden

Gomes, Maximiliano Schünke; Chagas, Patrícia; Padilha, Dalva Maria Pereira; Caramori, Paulo; Hugo, Fernando Neves; Schwanke, Carla Helena Augustin; Hilgert, Juliana Balbinot

doi:10.1590/s1806-83242012005000019

Cited by 25 publications

(31 citation statements)

References 28 publications

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“…Several epidemiologic investigations have suggested associations between poor oral health and adverse systemic outcomes, including mortality (73), cardiovascular diseases (54,(74)(75)(76)(77)(78), atherosclerosis (79), respiratory diseases (80,81), and other systemic conditions (46,(82)(83)(84). In order for these associations to be validated in future studies and in order for adequate interventional studies to be designed, the present study summarizes the evidence relating systemic markers of inflammation to endodontic infection.…”

Section: Discussionmentioning

confidence: 96%

Can Apical Periodontitis Modify Systemic Levels of Inflammatory Markers? A Systematic Review and Meta-analysis

Gomes

Blattner

Filho

et al. 2013

Journal of Endodontics

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184

162

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Section: Discussionmentioning

confidence: 96%

Can Apical Periodontitis Modify Systemic Levels of Inflammatory Markers? A Systematic Review and Meta-analysis

Gomes

Blattner

Filho

et al. 2013

Journal of Endodontics

Self Cite

184

162

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“…2,3 Both dental caries (decay) and periodontal disease (gum disease) are largely preventable, and even reversible in the early stages, 4,5 and the effects of poor oral health include cardiovascular disease and poorer general health. [5][6][7] As it progresses, oral disease can result in debilitating pain, difficulty eating and speaking, embarrassment and other negative effects.…”

Section: Introductionmentioning

confidence: 99%

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Silva¹,

Martin-Kerry

McKee³

et al. 2017

Aust. Health Review

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Objective. The aim of the present study was to identify all evidence about the prevalence and severity of clinically measured caries and periodontal disease in Indigenous adults in Australia published in peer-reviewed journals and to summarise trends over time. In addition, we examined whether the studies investigated associations between putative risk factors and levels of caries and periodontal disease.Methods. PubMed was searched in September 2014, with no date limitations, for published peer-reviewed articles reporting the prevalence rates and/or severity of caries and periodontal disease in Indigenous adults living in Australia. Articles were excluded if measurement was not based on clinical assessment and if oral disease was reported only in a specific or targeted sample, and not the general population.Results. The search identified 18 papers (reporting on 10 primary studies) that met the inclusion criteria. The studies published clinical data about dental caries and/or periodontal disease in Australian Indigenous adults. The studies reported on oral health for Indigenous adults living in rural (40%), urban (10%) and both urban and rural (50%) locations. Included studies showed that virtually all Indigenous adults living in rural locations had periodontal disease. The data also showed caries prevalence ranged from 46% to 93%. Although 10 studies were identified, the peer-reviewed literature was extremely limited and no published studies were identified that provided statistics for a significant proportion of Australia (Victoria, Tasmania, Queensland or the Australian Capital Territory). There were also inconsistencies in how the data were reported between studies, making comparisons difficult.Conclusions. This review highlights a lack of robust and contemporary data to inform the development of policies and programs to address the disparities in oral health in Indigenous populations living in many parts of Australia.What is known about the topic? Many studies report that Indigenous people in Australia have poorer general health compared with non-Indigenous people. What does this paper add? This paper documents the available caries and periodontal disease prevalence and experience for Indigenous adults in Australia published in peer-reviewed journals. It demonstrates significant limitations in the data, including no data in several large Australian jurisdictions, inconsistency with reporting methods and most data available being for Indigenous adults living in rural locations. Therefore, the oral health data available in the peer-reviewed literature do not reflect the situation of all Indigenous people living in Australia. What are the implications for practitioners? It is important for oral health practitioners to have access to current and relevant statistics on the oral health of Indigenous Australians. However, we have highlighted significant evidence gaps for this population group within the peer-reviewed literature and identified the limitations of the available data upon which INDIGENOUS HEAL...

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“…Tooth loss, which serves as a surrogate measure of history of oral disease, was also found independently associated with atherosclerosis and early mortality (Padilha et al . 2008, Gomes et al . 2012a).…”

Section: Introductionmentioning

confidence: 99%

Apical periodontitis and incident cardiovascular events in the Baltimore Longitudinal Study of Ageing

Gomes¹,

Hugo

Hilgert

et al. 2015

Int Endodontic J

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Aim To evaluate whether the presence of apical periodontitis (AP), root canal treatment (RCT) and endodontic burden (EB) – as the sum of AP and RCT sites – were associated with long-term risk of incident cardiovascular events (CVE), including cardiovascular-related mortality, using data on participants in the Baltimore Longitudinal Study of Aging (BLSA). Methodology This retrospective cohort included 278 dentate participants in the BLSA with complete medical and dental examinations. Periodontal disease (PD) and missing teeth were recorded. Total number of AP and RCT sites was determined from panoramic radiographs. EB was calculated as the sum of AP and RCT sites. Oral inflammatory burden (OIB) was calculated combining PD and EB. The main outcome was, incident CVE including angina, myocardial infarction and cardiovascular-related death. Participants were monitored for up to 44 years (mean=17.4±11.1 years) following dental examination. Relative Risks (RR) were calculated through Poisson regression models, estimating the relationship between AP, RCT, EB, PD, OIB and incident CVE. Results Mean age at baseline was 55.0±16.8 years and 51.4% were men. Sixty two participants (22.3%) developed CVE. Bivariate analysis showed that PD, EB, number of teeth and OIB were associated with incident CVE. Multivariate models, adjusted for socio-demographic and medical variables, showed that age≥60 years (RR=3.07, 95%CI=1.68-5.62), hypertension (RR=2.0, 95%CI=1.16-3.46) and EB≥3 (RR=1.77, 95%CI=1.04-3.02) were independently associated with incident CVE. The association between OIB and incident CVE was reduced to non-significance after adjustments (RR=1.97, 95%CI=0.83-4.70). Conclusions EB in mid-life was an independent predictor of CVE among community-dwelling participants in the BLSA. Prospective studies are required to evaluate cardiovascular risk reduction with the treatment of AP.

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Association between self-reported oral health, tooth loss and atherosclerotic burden

Cited by 25 publications

References 28 publications

Can Apical Periodontitis Modify Systemic Levels of Inflammatory Markers? A Systematic Review and Meta-analysis

Can Apical Periodontitis Modify Systemic Levels of Inflammatory Markers? A Systematic Review and Meta-analysis

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Apical periodontitis and incident cardiovascular events in the Baltimore Longitudinal Study of Ageing

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