Effects of emissions from sugar cane burning on the trachea and lungs of Wistar rats

Abstract

Objective:To evaluate the effects of exposure to emissions from sugar cane burning on inflammatory mechanisms in tissues of the trachea and lung parenchyma in Wistar rats after different periods of exposure. Methods:This was an experimental open randomized study. The animals were divided into four groups: a control group (CG) underwent standard laboratory conditions, and three experimental groups were exposed to emissions from sugar cane burning over different periods of time, in days-1 (EG1), 7 (EG7), and 21 (EG21). After euthanasia with 200 mg/kg of ketamine/xylazine, fragments of trachea and lung were collected and fixed in 10% formalin. Histological analyses were performed with H&E and picrosirius red staining. Results:No inflammatory infiltrates were found in the tissues of CG rats. The histological examination of tissues of the trachea and lung parenchyma revealed that the inflammatory process was significantly more intense in EG7 than in the CG (p < 0.05 and p < 0.01, respectively). In comparison with the CG and EG1, angiogenesis in the lung parenchyma and collagen deposition in tracheal tissues were significantly greater only in EG21 (p < 0.001 and p < 0.01, respectively). Conclusions:In this sample, emissions from sugar cane burning induced acute focal and diffuse inflammation in the lamina propria of tracheal tissues, with no loss of ciliated epithelial tissue. In the lung parenchyma of the animals in the experimental groups, there was interstitial and alveolar edema, together with polymorphonuclear cell infiltrates.

Protective effect of puerarin against burn‑induced heart injury in rats

“…For acute resuscitation, all rats in the S and B groups were intraperitoneally injected with lactated Ringer's solution (4 ml/kg/TBSA), whereas the BP and P groups were injected with 10 mg/kg/TBSA puerarin dissolved in lactated Ringer's solution (31) immediately after burn. The rats were then euthanized with 5% ketamine/xylazine (32), following which blood samples were collected by retroorbital exsanguination 12 h after burn treatment.…”

Economic impacts of bad output in agriculture: two essays for Brazilian sugarcane production

“…Historically, the sugarcane is planted in Brazil in a manual harvesting system, implementing the burning in the pre-harvesting period to remove the leaves, to help the manual harvesting of the stem, and to controll pests and weeds (Matos et al, 2017;Dinardo-Miranda and Fracasso, 2013). However, the pre-harvesting burning releases in the atmosphere particulate matters and gases, like carbon monoxide and carbon dioxide, that contribute to increase public health problems .…”