Reversed halo sign in invasive fungal infections

Marchiori, Edson; Hochhegger, Bruno; Zanetti, Gláucia

doi:10.1590/s1806-37562016000000119

Cited by 7 publications

(4 citation statements)

References 5 publications

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“…(4,(83)(84)(85)(86) As causas infecciosas mais comuns são a tuberculose, a paracoccidioidomicose e as doenças fúngicas invasivas (aspergilose pulmonar invasiva e mucormicose). (87) Entre as causas não infecciosas, a mais comum é a PO, tanto na sua forma idiopática como na forma secundária. Outras causas importantes são o enfarto pulmonar e a sarcoidose (Figura S34).…”

Section: Sinal Do Halo Invertidounclassified

Consensus statement on thoracic radiology terminology in Portuguese used in Brazil and in Portugal

et al. 2021

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Effective communication among members of medical teams is an important factor for early and appropriate diagnosis. The terminology used in radiology reports appears in this context as an important link between radiologists and other members of the medical team. Therefore, heterogeneity in the use of terms in reports is an important but little discussed issue. This article is the result of an extensive review of nomenclature in thoracic radiology, including for the first time terms used in X-rays, CT, and MRI, conducted by radiologists from Brazil and Portugal. The objective of this review of medical terminology was to create a standardized language for medical professionals and multidisciplinary teams.

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Section: Sinal Do Halo Invertidounclassified

Consensus statement on thoracic radiology terminology in Portuguese used in Brazil and in Portugal

et al. 2021

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“…The clinical presentation is difficult to distinguish from invasive pulmonary aspergillosis 180,181 . A so‐called reversed halo sign has been described on computed tomography scans, but is not entirely specific for mucormycosis 182‐184 . Such ring‐shaped consolidation surrounding a central infiltrate should prompt a diagnostic work‐up including bronchoalveolar lavage and biopsy 8,185 …”

Section: Resultsmentioning

confidence: 99%

“…180,181 A socalled reversed halo sign has been described on computed tomography scans, but is not entirely specific for mucormycosis. [182][183][184] Such ring-shaped consolidation surrounding a central infiltrate should prompt a diagnostic work-up including bronchoalveolar lavage and biopsy. 8,185 Treatment combines surgical debridement and antifungal treatment (AII).…”

Section: Treatment Of Mucormycosismentioning

confidence: 99%

Treatment of invasive fungal diseases in cancer patients—Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Ruhnke

Cornely

Schmidt‐Hieber

et al. 2020

Mycoses

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Summary Background Invasive fungal diseases remain a major cause of morbidity and mortality in cancer patients undergoing intensive cytotoxic therapy. The choice of the most appropriate antifungal treatment (AFT) depends on the fungal species suspected or identified, the patient's risk factors (eg length and depth of granulocytopenia) and the expected side effects. Objectives Since the last edition of recommendations for ‘Treatment of invasive fungal infections in cancer patients’ of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) in 2013, treatment strategies were gradually moving away from solely empirical therapy of presumed or possible invasive fungal diseases (IFDs) towards pre‐emptive therapy of probable IFD. Methods The guideline was prepared by German clinical experts for infections in cancer patients in a stepwise consensus process. MEDLINE was systematically searched for English‐language publications from January 1975 up to September 2019 using the key terms such as ‘invasive fungal infection’ and/or ‘invasive fungal disease’ and at least one of the following: antifungal agents, cancer, haematological malignancy, antifungal therapy, neutropenia, granulocytopenia, mycoses, aspergillosis, candidosis and mucormycosis. Results AFT of IFDs in cancer patients may include not only antifungal agents but also non‐pharmacologic treatment. In addition, the armamentarium of antifungals for treatment of IFDs has been broadened (eg licensing of isavuconazole). Additional antifungals are currently under investigation or in clinical trials. Conclusions Here, updated recommendations for the treatment of proven or probable IFDs are given. All recommendations including the levels of evidence are summarised in tables to give the reader rapid access to key information.

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“…gschiappacasse@gmail.com E l signo del halo invertido se caracteriza por una opacidad central de vidrio esmerilado rodeada por una consolidación del espacio aéreo más densa en forma de una media luna o un anillo. Inicialmente esto fue descrito como un signo específico para la neumonía organizada criptogénica 1,2 , posteriormente, el signo del halo invertido se ha informado en asociación con una amplia gama de enfermedades pulmonares, de etiología benigna o maligna, en inmunocompetentes o inmunodeprimidos, incluidas las infecciones fúngicas pulmonares invasivas, para coccidioidomicosis, neumonía por Pneumocystis jirovecii, tuberculosis, neumonía adquirida en la comunidad, granulomatosis linfomatoidea, granulomatosis de Wegener, neumonía lipoidea y sarcoidosis 1,2,4 . También se puede observar en neoplasias pulmonares e infarto, luego de radioterapia y ablación por radiofrecuencia de neoplasias malignas pulmonares 2 .…”

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Signo del halo invertido como manifestación inhabitual de neumonía organizada criptogénica. Reporte de un caso

et al. 2019

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Reversed halo sign as an unusual manifestation of cryptogenic organized pneumonia. Report of one case We report a 64 years old female admitted with fever, cough, dyspnea and lung opacities in the chest X ray. A chest tomography scan (CTS) showed multiple-bilateral ring-shaped opacities and the reversed halo sign (RHS). The patient did not improve with antimicrobial therapy (AT). Infection and rheumatologic causes were excluded, therefore Cryptogenic organizing pneumonia (COP) was suspected with compatible percutaneous biopsy. Systemic steroids were started with a good clinical response. The patient was discharged four weeks after admission in good general conditions and practically no lungs opacities.

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Reversed halo sign in invasive fungal infections

Cited by 7 publications

References 5 publications

Consensus statement on thoracic radiology terminology in Portuguese used in Brazil and in Portugal

Consensus statement on thoracic radiology terminology in Portuguese used in Brazil and in Portugal

Treatment of invasive fungal diseases in cancer patients—Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Signo del halo invertido como manifestación inhabitual de neumonía organizada criptogénica. Reporte de un caso

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