Oxygen desaturation during the six-minute walk test in COPD patients

Moreira, Maria Angela Fontoura; Medeiros, Gabriel Arriola de; Boeno, Francesco Pinto; Sanches, Paulo Roberto Stefani; Júnior, Danton Pereira da Silva; Müller, André Frotta

doi:10.1590/s1806-37132014000300004

Cited by 26 publications

(18 citation statements)

References 16 publications

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“…The BODE is considered an index of multidimensional (24,25), classification of the severity of COPD (26,27) where a score of 3 points or more is associated 3 to 4 points; Quartile III: 5 to 6 points; Quartile IV: 7 to 10 points.…”

Section: Resultsmentioning

confidence: 99%

Handgrip and functional capacity in Chronic Obstructive Pulmonary Disease patients

et al. 2017

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Introduction: In the Chronic Obstructive Pulmonary Disease (COPD) both pulmonary and systemic condition increase dyspnea, intolerance to exercise and inactivity. Objective: To evaluate possible association between Hand Grip Strength (HGS) and the distance covered in the Six-Minute Walk Test (6MWT) in patients with Chronic Obstructive Pulmonary Disease (COPD). Methods: A cross-sectional study that evaluated 34 patients with COPD from moderate to very severe stages. The HGS test was performed with a manual hydraulic dynamometer (Jamar®, California, USA) with three bilateral measures, allowing

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Section: Resultsmentioning

confidence: 99%

Handgrip and functional capacity in Chronic Obstructive Pulmonary Disease patients

et al. 2017

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“…Functional status assessment revealed that walk distance in patients with BAF was significantly lower as compared to those with anthracosis only. In addition, on 6MWT more than half the BAF patients (58.3%) desaturated with a fall in SpO 2 ≥ 4% from the baseline which was considered significant [11]. On functional assessment, patients with BAF fared poorer than those with anthracosis, a finding which is yet to be documented in the literature.…”

Section: Discussionmentioning

confidence: 96%

“…Patients in Group 1 walked significantly lesser distance as compared to Group 2 (p = 0.003) but there was no significant difference between Groups 1 and 3 (p = 0.41) and Groups 2 and 3 (p = 0.09). In Group 1, significant desaturation (a fall in SpO 2 ≥ 4% from the baseline) [11] was seen in 14/24 (58%) patients, in Group 2 6/17 (35.3%) and in Group 3 6/19 (31.6%).…”

Section: Six Minute Walk Test (6mwt)mentioning

confidence: 97%

Occurrence of Bronchial Anthracofibrosis in Respiratory Symptomatics with Exposure to Biomass Fuel Smoke

Pilaniya

Kunal

Shah

2017

Advances in Respiratory Medicine

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Introduction: Bronchial anthracofibrosis (BAF), confirmed bronchoscopically, is characterised by bluish-black mucosal pigmentation and distortion/narrowing of the bronchus. We investigated the occurrence of BAF in respiratory symptomatics with biomass fuel smoke exposure and evaluated its clinico-radiological attributes and impact on functional status. Material and methods: Of the eighty subjects evaluated, 60 consented for fiberoptic bronchoscopy (FOB). All 60 subjects also underwent chest radiography, high resolution computed tomography (HRCT) of the thorax, spirometry with reversibility testing and six-minute-walk test. Information regarding cardinal respiratory symptoms and duration of biomass fuel smoke exposure was documented. FOB evaluation revealed that 24 patients had BAF (Group 1), 17 had bronchial anthracosis (Group 2) and 19 had normal appearance (Group 3). Results: Group 1 patients had significantly higher biomass fuel smoke exposure (p < 0.0001) and lower walk distance (p = 0.003) with greater desaturation. On HRCT, segmental collapse and consolidation were significantly higher in Group 1 while fibrotic lesions were the predominantly seen in Groups 2 and 3. A significant inverse correlation in Group 1 was seen between exposure index, six-minute-walk distance and spirometric parameters. In Group 1, the right middle lobe (RML) bronchus was most commonly involved (15/24 [62.5%]). In Group 2, RML and left upper lobe bronchi were affected in 8/17 (47.1%) patients each. Conclusions: All patients in our study were females. Those with BAF had poorer functional status as compared to those with anthracosis only. On imaging, multifocal bronchial narrowing was specific to BAF.

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“…We also observed patients who showed a reduction in SpO 2 > 4% from baseline, whether or not the resultant SpO 2 was less than 94% (13). Even though this latter criterion is often used in quantifying the severity of obstructive sleep apnoea in sleep studies (14), it has also been used for assessment of patients with chronic obstructive pulmonary diseases (COPD) and in the context of endoscopic procedures (15,16).…”

Section: Discussionmentioning

confidence: 99%

Incidence of Maternal Desaturation among Patients Undergoing Elective Caesaraen Section under Regional Anaesthesia

Yee¹

2017

JSA

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This was a prospective observational study to identify the incidence and possible risk factors for maternal desaturation following neuraxial blockade for elective caesarean section (CS). Patients with body mass index (BMI) ≥ 30 kg/m 2 at the first antenatal consultation were identified and classified into the obese group. Neuraxial blockade in the form of subarachnoid block (SAB) or combined spinal-epidural (CSE) was performed. Mean arterial pressure (MAP) and oxygen saturation (SpO 2 ) were recorded at baseline and at 5-minute intervals following neuraxial blockade. Desaturation, defined as SpO 2 < 94% for more than 30 seconds without artifacts, was managed with oxygen therapy and other appropriate measures. Newborn Apgar score and umbilical cord blood gases were analysed. Among a total of 254 recruited patients, 69 (27.2%) were obese and were associated with significantly higher age, parity, previous CS and pre-existing diabetes mellitus. The incidence of oxygen desaturation was 1.2%, involving three patients in the non obese group. These desaturation episodes were short-lived and associated with intraoperative hypotension. Six patients, two of whom in the obese group, received rescue oxygen therapy following intraoperative events such as deteriorating SpO 2 or hypotension. The mean MAP was significantly lower at baseline and at 5 minutes post neuraxial blockade in the non obese group, which could account for the occurrence of desaturation in this group only. There were no significant inter-group differences in terms of neonatal outcome, umbilical cord blood gases and changes in mean SpO 2 post neuraxial blockade. In conclusion, the current practice of not routinely giving supplementary oxygen to patient during elective CS at our institution is deemed to be safe, provided continuous SpO 2 monitoring is available throughout the surgery. Further randomised clinical trials are indicated to investigate the impact of maternal obesity and of labouring patients presenting for urgent or emergency CS on intraoperative oxygen desaturation.

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Oxygen desaturation during the six-minute walk test in COPD patients

Cited by 26 publications

References 16 publications

Handgrip and functional capacity in Chronic Obstructive Pulmonary Disease patients

Handgrip and functional capacity in Chronic Obstructive Pulmonary Disease patients

Occurrence of Bronchial Anthracofibrosis in Respiratory Symptomatics with Exposure to Biomass Fuel Smoke

Incidence of Maternal Desaturation among Patients Undergoing Elective Caesaraen Section under Regional Anaesthesia

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