Tiotropium use and pulmonary function in patients with constrictive bronchiolitis

Kawassaki, Alexandre de Melo; Kawano-Dourado, Letícia; Kairalla, Ronaldo Adib

doi:10.1590/s1806-37132014000100014

Cited by 5 publications

(4 citation statements)

References 4 publications

(10 reference statements)

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“…The illness rarely occurred after a reported history of respiratory infection or as a result of a suspected paraneoplastic etiology. Among series that reported on smoking, 4 , 5 , 7 , 8 , 9 , 10 , 11 , 12 21% of patients had a history of smoking. The previous series did not report the incidence of GERD.…”

Section: Resultsmentioning

confidence: 99%

“…Among the published literature, 5 series reported at least some CT findings on a total of 68 patients. 8 , 9 , 10 , 11 , 12 These studies are heterogeneous with respect to the reported CT findings, because (a) not all reported on the presence of all CT abnormalities; (b) the presence of mosaic ground glass and air trapping were part of the inclusion criteria in 1 study 11 ; and (c) previous series reported only on the presence, but not the extent, of each abnormality. These caveats notwithstanding, evidence of air trapping on expiratory images was a universal feature in patients with OB in the literature.…”

Section: Resultsmentioning

confidence: 99%

“…We searched the National Library of Medicine's PubMed, the Cochrane Central Register of Controlled Trials, MEDLINE, PubMed Central, and EMBASE databases with the search terms “constrictive bronchiolitis,” “obliterative bronchiolitis,” and “bronchiolitis obliterans,” excluding publications linked with “transplantation” and “organizing pneumonia.” The results were refined to English language series that reported 3 or more adults, and excluded point outbreaks. This generated 104 separate cases, 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 published between 1981 and 2014 (see Supplemental Figure ).…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Sporadic Obliterative Bronchiolitis: Case Series and Systematic Review of the Literature

Callahan

Vranic

Flors

et al. 2019

Mayo Clinic Proceedings: Innovations, Quality & Outcomes

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ObjectiveTo describe the clinical characteristics and outcomes of patients diagnosed with obliterative bronchiolitis (OB) not associated with transplantation or point-source exposures to inhaled toxins.Patients and MethodsWe compiled all confirmed diagnoses of OB at our institution and analyzed their demographic characteristics, treatments, and outcomes as defined by pulmonary function tests (PFTs) and transplant-free mortality. The study period ranged from July 2007 to August 2017. Histological diagnosis was confirmed by a pathologist, and high-resolution chest computed tomography (CT) scans were reviewed and scored by chest radiologists. We also performed a systematic literature review of sporadic OB series.ResultsWe identified 19 confirmed cases at our institution and 9 publications in the literature containing 104 patients. In both our series and the literature, patients were disproportionately middle-aged Caucasian women. The disease was idiopathic in 42% and was associated with connective tissue diseases and inhalational exposures in 31% and 15%, respectively. Chest CT showed expiratory air trapping in all patients. Patients were treated with corticosteroids, steroid-sparing agents, and macrolides in 77%, 46%, and 22%, respectively. Over a median follow-up in our series of 1703 days (range, 11-3206 days), PFTs did not change significantly. In all series combined, mortality incidence from any cause was 82/1000 patient-years (95% CI, 65-102). Of 14 patients who died, 3 deaths were due to respiratory failure and 5 were potentially related to complications of immunosuppressive therapy.ConclusionSporadic OB is a rare disease that is uniformly associated with air trapping on high-resolution chest CT. The diagnosis should be established with surgical biopsy if possible. The illness is not typically progressive.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Sporadic Obliterative Bronchiolitis: Case Series and Systematic Review of the Literature

Callahan

Vranic

Flors

et al. 2019

Mayo Clinic Proceedings: Innovations, Quality & Outcomes

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show abstract

“…64,65 Uma série de casos do nosso serviço mostrou melhora significativa da CVF e do VEF1 em pacientes portadores de BC de diversas etiologias, sendo que 2 deles eram portadores de AR. 66 Nos casos mais leves está autorizada a observação clínica. 18 O prognóstico da BC idiopática é, em geral, reservado, culminando com insuficiência respiratória grave.…”

Section: Bronquiolite Constritivaunclassified

Espirometria em pacientes portadores de artrite reumatoide e sua associação com aspectos epidemiológicos, clínicos, radiológicos e tratamento

Kawassaki¹

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Bronchiolitis Obliterans

Vos

Schoemans

Vanaudenaerde

et al. 2016

Encyclopedia of Inflammatory Diseases

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Tiotropium use and pulmonary function in patients with constrictive bronchiolitis

Cited by 5 publications

References 4 publications

Sporadic Obliterative Bronchiolitis: Case Series and Systematic Review of the Literature

Sporadic Obliterative Bronchiolitis: Case Series and Systematic Review of the Literature

Espirometria em pacientes portadores de artrite reumatoide e sua associação com aspectos epidemiológicos, clínicos, radiológicos e tratamento

Bronchiolitis Obliterans

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