Casos confirmados de influenza em pacientes hospitalizados com suspeita de infecção por influenza A (H1N1) em 2010 em um hospital sentinela na cidade de São Paulo

Melchior, Thaís Boim; Guatura, Sandra Baltazar; Camargo, Clarice Neves; Watanabe, Aripuanã Sakurada Aranha; Granato, Celso Francisco Hernandes; Bellei, Nancy

doi:10.1590/s1806-37132011000500013

Cited by 3 publications

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“…Mais um artigo descreve os antecedentes históricos da pandemia de influenza por novo subtipo viral e sintetiza as informações sobre medidas a serem tomadas com os casos e contactantes, bem como sinais, sintomas e tratamento (Machado, 2009 (Abdulkader et al, 2010;Bianco et al, 2011;Bellei, 2012;Carmona et al, 2011;Cerbino Neto;Werneck, 2013;Duarte et al, 2009;Fawkner-Corbett et al, 2012;Figueiró-Filho et al, 2012;Freitas et al, 2009;Greco;Tupinambás;Fonseca, 2009;Guatura et al, 2012;Jimenez et al, 2010;Pontarolo, 2012;Pontarolo, 2013;Lenzi et al, 2011Lenzi et al, , 2012aLenzi et al, , 2012bMelchior et al, 2011;Nassar Junior et al, 2010;Oliveira et al, 2009;Pires Neto et al, 2013;Raboni et al, 2011;Ribeiro et al, 2010; SP/SES/CCD/CVE, 2009; Saraceni et al, 2010;Schout et al, 2009;Schuelter-Trevisol et al, 2012;Yokota et al, 2011). Considerando estes critérios, tentamos recuperar a história da pandemia por influenza A(H1N1)pdm09 no Brasil, centrada no conjunto da caracterização epidemiológica e morbimortalidade dos casos.…”

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Estudo descritivo da pandemia da Influenza A(H1N1)pdm09 no Brasil, 2009-2010

Rossetto¹

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Estudo descritivo da pandemia da Influenza A(H1N1)pdm09 no Brasil, 2009-2010

Rossetto¹

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A Descriptive Study of Pandemic Influenza A(h1n1)pdm09 in Brazil, 2009 - 2010

Rossetto

Luna

2016

Rev. Inst. Med. trop. S. Paulo

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SUMMARYInfluenza A viruses undergo frequent antigenic mutations and may thus cause seasonal epidemics and pandemics. The aim of this study was to recover the epidemiological history of the pandemic influenza A(H1N1)pdm09 in Brazil. A descriptive study was conducted in 2009-2010. The Brazilian Information System for reportable diseases (SINAN) was the data source. A total of 105,054 suspected cases of influenza A(H1N1)pdm09 were reported to SINAN. Of these, 53,797 (51.2%) were classified as the new influenza virus subtype. Among the confirmed cases, 56.7% were female, the mean age was 26.31 (SD ± 18.1) years. Fever was the most common sign among the confirmed cases (99.7%) and the presence of comorbidities was reported in 32.5% of cases. In 2009 there were confirmed cases in all 26 Brazilian States and the Federal District. The incidence (per 100,000 inhabitants) of severe influenza in the population was 28.0 in 2009 and 0.5 in 2010. The states of Paraná (301.3), Santa Catarina (36.0) and Rio Grande do Sul (27.4) presented the highest incidence; 46.4% of the confirmed cases were hospitalized and 47,643 were cured (93.8%). The case-fatality rate was 3.9% in 2009. The pandemic virus A(H1N1)pdm09 hit Brazil between April/2009 and December/2010 with an important difference in the geographic pattern distribution of the cases from the northeast to the south of the country. Children and young adults were the most affected. The limitations of the study were data quality and inconsistencies in the final classification of cases in SINAN. This study highlights the urgent need for improvements in the surveillance of emerging diseases in Brazil.

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Clinical aspects of influenza A(H1N1)pdm09 cases reported during the pandemic in Brazil, 2009-2010

Rossetto

Luna

2015

Einstein (São Paulo)

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Objective:To describe the clinical aspects of cases of influenza A(H1N1)pdm09 in Brazil.Methods:A descriptive study of cases reported in Sistema de Informação de Agravos de Notificação (SINAN), 2009-2010.Results:As the final classification, we obtained 53,797 (56.79%) reported cases confirmed as a new influenza virus subtype, and 40,926 (43.21%) cases discarded. Fever was the most common sign, recorded in 99.74% of the confirmed and 98.92% of the discarded cases. Among the confirmed cases, the presence of comorbidities was reported in 32.53%, and in 38.29% of the discarded cases. The case fatality rate was 4.04%; 3,267 pregnant women were confirmed positive for influenza A new viral subtype and 2,730 of them were cured. The case fatality rate of pregnant women was 6.88%.Conclusion:The findings suggested concern of the health system with pregnant women, and patients with comorbidities and quality of care may have favored a lower mortality. We recommend that, when caring for patients with severe respiratory symptoms, with comorbidities, or pregnant women, health professionals should consider the need for hospital care, as these factors make up a worse prognosis of infection by the pandemic influenza virus.

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Casos confirmados de influenza em pacientes hospitalizados com suspeita de infecção por influenza A (H1N1) em 2010 em um hospital sentinela na cidade de São Paulo

Cited by 3 publications

References 3 publications

Estudo descritivo da pandemia da Influenza A(H1N1)pdm09 no Brasil, 2009-2010

Estudo descritivo da pandemia da Influenza A(H1N1)pdm09 no Brasil, 2009-2010

A Descriptive Study of Pandemic Influenza A(h1n1)pdm09 in Brazil, 2009 - 2010

Clinical aspects of influenza A(H1N1)pdm09 cases reported during the pandemic in Brazil, 2009-2010

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