Hemangioma subglótico e mediastinal em criança: tratamento com propranolol

In this cohort of at-risk infants, topical timolol appeared to provide safe treatment for IHs in full-term infants receiving a dose of less than 0.2 mg/kg/day, but infants with a PMA of less than 44 weeks and weight at treatment initiation of less than 2,500 g may be at risk of adverse events, including bradycardia, hypotension, apnea, and hypothermia. We recommend close monitoring of temperature, blood pressure, and heart rate in premature and low-birthweight infants with IHs at initiation of and during therapy with topical timolol.

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Mediastinal and subglottic hemangioma in an infant: a case report and literature review

Lin

Hai²,

Chen³

et al. 2021

J Int Med Res

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We performed a retrospective analysis of the clinical manifestations, laboratory and imaging examinations, treatment, and prognosis of a male infant who was diagnosed with mediastinal and subglottic hemangioma in our hospital. The clinical features of this patient were coughing, wheezing, and dyspnea. Enhanced computed tomography of the neck and chest showed a diffuse abnormality in the right-upper mediastinum. He was diagnosed with a hemangioma after a physical examination combined with bronchoscopy. The clinical symptoms were relieved by oral propranolol. We also investigated the clinical characteristics, treatment, and prognosis of mediastinal and subglottic hemangioma in infants in the previous literature, and searched for case reports of this disease in China and in other countries. We only identified three previous cases of mediastinal and subglottic hemangioma in infants, indicating that this condition is rare. In the proliferative stage, surrounding organs and tissues are compressed, which can be life-threatening. Most of these children develop wheezing, shortness of breath, dyspnea, cyanosis, and other symptoms within 2 months. Enhanced computed tomography and magnetic resonance imaging combined with soft bronchoscopy can confirm the diagnosis of this disease, and oral propranolol achieves a favorable effect.

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Hemangioma subglótico e mediastinal em criança: tratamento com propranolol

Cited by 5 publications

References 4 publications

The use of propranolol in the treatment of subglottic hemangiomas: A literature review and meta-analysis

The use of propranolol in the treatment of subglottic hemangiomas: A literature review and meta-analysis

Adverse Events in Young and Preterm Infants Receiving Topical Timolol for Infantile Hemangioma

Mediastinal and subglottic hemangioma in an infant: a case report and literature review

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