As novas perspectivas do transplante de pulmão: da preservação convencional à perfusão pulmonar ex vivo com recondicionamento pulmonar

Cardoso, Paulo Francisco Guerreiro

doi:10.1590/s1806-37132009001100001

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…( 3 ) The most common indications for this intervention are emphysema (in 36%), idiopathic pulmonary fibrosis (in 20%), and cystic fibrosis (in 16%). ( 4 ) In transplantation candidates, assessment of their level of physical activity is an important tool for quantifying the impact of the disease on their activities of daily living (ADL). ( 5 ) …”

Section: Introductionmentioning

confidence: 99%

Aplicabilidade da escala London Chest Activity of Daily Living em pacientes em lista de espera para transplante de pulmão

Müller

Gonçalves²,

Fontoura³

et al. 2013

J. bras. pneumol.

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OBJECTIVE: To evaluate the applicability of the London Chest Activity of Daily Living (LCADL) scale in patients on the waiting list for lung transplantation. METHODS: This was a cross-sectional study, conducted between May and September of 2010, involving 26 male and female patients on the waiting list for lung transplantation and treated at the Pulmonary Rehabilitation Program in the Complexo Hospitalar Santa Casa de Misericórdia de Porto Alegre, located in the city of Porto Alegre, Brazil. We evaluated the patients using the six-minute walk test (6MWT) and pulmonary function tests. We also obtained the LCADL scores, as well as the modified Borg scale scores for sensation of dyspnea and leg fatigue. Cronbach's alpha coefficient was used to determine the internal consistency of the LCADL scale. Linear regression analysis was used in order to identify associations between the total LCADL score (expressed as a percentage) and the variables studied. RESULTS: According to the LCADL scale results, 69% of the patients reported that the performance of their activities of daily living was significantly impaired by their dyspnea. The internal consistency of the LCADL scale was 0.89. After adjusting for age and FEV1, we found that the total LCADL scale score showed statistically significant negative associations with the six-minute walk distance (β = −0.087; p < 0.001) and the six-minute walk work (β = −0.285; p < 0.001). CONCLUSIONS: Our findings suggest that the LCADL scale is a useful tool for assessing patients on the waiting list for lung transplantation.

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Section: Introductionmentioning

confidence: 99%

Aplicabilidade da escala London Chest Activity of Daily Living em pacientes em lista de espera para transplante de pulmão

Müller

Gonçalves²,

Fontoura³

et al. 2013

J. bras. pneumol.

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“…45 Estudos já comprovaram que a perfusão ex vivo do órgão melhora as condições metabólicas do enxerto e o sucesso do transplante, incluindo uma diminuição da carga de microrganismos do órgão. [46][47][48][49][50][51][52][53][54][55][56][57][58][59] O desenvolvimento instrumental e do protocolo de irradiação UV-C associado à máquina de perfusão ex vivo de pulmão e rim foi reportado recentemente pelo nosso grupo. [60][61][62] Outra técnica muito bem conhecida usada na inativação de microrganismos patogênicos é a terapia fotodinâmica (TFD) ou também chamada inativação fotodinâmica (IFD) ou terapia fotodinâmica antimicrobiana (TFDa) nos estudos que visam o controle microbiológico.…”

Section: Introductionunclassified

Avaliação de técnicas ópticas para descontaminação de órgãos sólidos para transplante em modelos >i<in vitro>/i< e >i<ex vivo>/i<

Gámez¹

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Agradezco a Dios todo poderoso, en su infinita bondad, por mi vida, por guiarme e iluminar mi camino, por darme fuerzas para seguir adelante cuando creía que todo estaba perdido.A toda mi familia, en especial a mis padres Mirna y Riquildo y hermana Yoandra, por su apoyo incondicional, dedicación y amor. A mi princesita Tábatha por brindarme tanto amor y ser el motor impulsor que me da fuerzas para seguir adelante y sobrepasar todos los obstáculos.A mi esposo Luis Carlos por su apoyo incondicional, amor y comprensión. Por ser mi compañero y amigo, por ayudarme a levantar cuando estaba perdiendo las fuerzas para continuar adelante con mis proyectos.A mis amigos Loraine, Erika, Camilinha, Johan y mi madrina Eunice, los cuales forman parte de mi familia; que siempre han estado conmigo en los buenos y malos momentos, dándome su apoyo incondicional.A Jose Dirceu, por sus consejos y ayuda durante todo el doctorado, mostrándome que siempre es posible, que después de la tormenta, llega la calma.A la profesora Cristina Kurachi por ser mi orientadora y por darme la oportunidad de formar parte del grupo de pesquisa; por el soporte científico, análisis y sugerencias que fueron de extrema importancia para el desenvolvimiento de la pesquisa y por ser, además de orientadora, amiga.Al profesor Vanderlei y Natalia por su ayuda, contribución científica e incentivo a mi crecimiento profesional.A los integrantes del grupo de descontaminación de órganos: José Dirceu, Caroline, Loraine y de forma general a todos los colegas del grupo de Biofotónica que de una forma u otra contribuyeron al desenvolvimiento de la pesquisa.

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Comparison Between Perfadex and Locally Manufactured Low-Potassium Dextran Solution for Pulmonary Preservation in an Ex Vivo Isolated Lung Perfusion Model

Soares

Braga

Nepomuceno

et al. 2011

Transplantation Proceedings

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Lungs preserved for 24 hours were nonviable and therefore excluded from the analysis. Those preserved for 6 hours showed better ventilatory mechanics when compared with 12 hours. The oxygenation capacity was not different between lungs flushed with LPD or LPDnac, regardless of the ischemic time. SAL lungs showed higher PCO(2) values than the other solutions. Lung weight increased over time during perfusion; however, there were no significant differences among the tested solutions (LPD, P = .23; LPDnac, P = .41; SAL, P = .26). We concluded that the LPDnac solution results in gas exchange were comparable to the original LPD (Perfadex); however ventilatory mechanics and edema formation were better with LPD, particularly among lungs undergoing 6 hours of cold ischemia.

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As novas perspectivas do transplante de pulmão: da preservação convencional à perfusão pulmonar ex vivo com recondicionamento pulmonar

Cited by 4 publications

References 10 publications

Aplicabilidade da escala London Chest Activity of Daily Living em pacientes em lista de espera para transplante de pulmão

Aplicabilidade da escala London Chest Activity of Daily Living em pacientes em lista de espera para transplante de pulmão

Avaliação de técnicas ópticas para descontaminação de órgãos sólidos para transplante em modelos >i<in vitro>/i< e >i<ex vivo>/i<

Comparison Between Perfadex and Locally Manufactured Low-Potassium Dextran Solution for Pulmonary Preservation in an Ex Vivo Isolated Lung Perfusion Model

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