Tratamento da actinomicose pulmonar com levofloxacina

Abstract

Actinomycosis is a chronic suppurative bacterial infection characterized by multiple abscesses, fistulous pathways, and fibrosis involving the face, neck, chest, and abdomen. It is caused by an anaerobic Gram-positive saprophytic bacterium (Actinomyces). Primary actinomycosis of the lung is a rare disease that probably results from aspiration of oropharyngeal secretions. It can present as a chronic respiratory disease. The treatment of choice is antibiotic therapy with penicillin. The authors report the case of a 55-year-old female diagnosed with pulmonary actinomycosis and successfully treated with levofloxacin.Keywords: Actinomycosis; Infection; Ofloxacin; Medical records. ResumoA actinomicose é uma infecção bacteriana supurativa crônica caracterizada por múltiplos abcessos, trajetos fistulosos e fibrose envolvendo a face, o pescoço, o tórax e o abdômen. É causada por uma bactéria anaeróbia, Gram-positiva e saprófita (Actinomyces). A actinomicose pulmonar primária é uma doença rara que resulta provavelmente da aspiração de secreções da orofaringe. Pode apresentar-se como uma doença respiratória crônica. O tratamento de escolha é a antibioticoterapia com penicilina. Os autores apresentam o caso clínico de uma mulher de 55 anos com diagnóstico de actinomicose pulmonar tratada com sucesso com levofloxacina.

A Case Report of Pelvic Actinomycosis and a Literature Review

“…The 3 most common symptoms of pelvic actinomycosis are abdominal pain, weight loss, and abnormal vaginal discharge. It is reported that 60% of patients also have fever, and the clinical manifestations are less severe than the lesion [ 11 , 12 ]. In severe cases, a sinus tract or fistula is formed, and solid masses with fixed and unclear boundaries are formed, and even “frozen pelvis” can occur.…”

Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature

“…Although Actinomyces reside in the oropharynx and gastrointestinal tract, and are normally avirulent in healthy individuals (5,6), Actinomyces -associated diseases can occur in individuals with particular host characteristics [e.g., aspiration, alcohol abuse, periodontal disease, chronic obstructive pulmonary disease (COPD), and diabetes mellitus] (7). Pulmonary actinomycosis is relatively rare (8), and is thought to result from the aspiration of Actinomyces into the lungs (9). Although chest imaging of pulmonary actinomycosis most commonly reveals fibrotic infiltrates that are confined to a single lobe with small cavitary lesions (10), non-specific findings are commonly observed in clinical practice (11-13).…”