A farmacoeconomia e o tratamento da asma

Jardim, José Roberto

doi:10.1590/s1806-37132007000100002

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…( 71 - 73 ) It is speculated that OSAS plays an important role in asthma exacerbations and that the use of CPAP can decrease exacerbations, improve quality of life, and reduce the number of cases of difficult-to-control asthma. ( 74 ) Chan et al ( 75 ) noted that the mean pre-bronchodilator and post-bronchodilator FEV 1 were higher during CPAP therapy than during two control periods (i.e., without CPAP therapy).…”

Section: Prospects For Intervention In Osas-asthmamentioning

confidence: 99%

“…( 71 - 73 ) Especula-se que a SAOS pode ser um fator importante nas exacerbações de asma e que o uso de CPAP poderia reduzir as exacerbações, melhorar a qualidade de vida e reduzir o número de casos de asma de difícil controle. ( 74 ) Chan et al ( 75 ) observaram que a média do VEF 1 pré e pós-broncodilatador foi maior durante o intervalo durante a terapia com CPAP quando comparada entre dois períodos sem CPAP.…”

Section: Perspectivas De Intervenção Sobre O Binômio Saos-asmaunclassified

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Obstructive sleep apnea and asthma

et al. 2013

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Symptoms of sleep-disordered breathing, especially obstructive sleep apnea syndrome (OSAS), are common in asthma patients and have been associated with asthma severity. It is known that asthma symptoms tend to be more severe at night and that asthma-related deaths are most likely to occur during the night or early morning. Nocturnal symptoms occur in 60-74% of asthma patients and are markers of inadequate control of the disease. Various pathophysiological mechanisms are related to the worsening of asthma symptoms, OSAS being one of the most important factors. In patients with asthma, OSAS should be investigated whenever there is inadequate control of symptoms of nocturnal asthma despite the treatment recommended by guidelines having been administered. There is evidence in the literature that the use of continuous positive airway pressure contributes to asthma control in asthma patients with obstructive sleep apnea and uncontrolled asthma.

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Section: Prospects For Intervention In Osas-asthmamentioning

confidence: 99%

Section: Perspectivas De Intervenção Sobre O Binômio Saos-asmaunclassified

Obstructive sleep apnea and asthma

et al. 2013

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The problem of obstructive sleep apnea syndrome in asthmatic patients

Sheludko

Naumov

Perelman

et al. 2017

Terapevticheskii arkhiv

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Asthma and obstructive sleep apnea syndrome (OSAS) are one of the most common chronic respiratory diseases. These have common risk factors that include obesity, gastroesophageal reflux disease (GERD) and impaired nasal breathing (allergic rhinitis, sinusitis). At the same time, experimental evidence demonstrates common pathophysiological mechanisms of these diseases, such as involvement in the process of the respiratory tract, a systemic inflammatory response, and implementation of neuromechanical reflexes. Thus, there is an obvious synergism between these conditions, which affects symptoms, response to therapy, and prognosis. The available data allow discussion on whether there is a need to identify and treat OSAS in asthmatic patients. By keeping in mind the high incidence of OSAS in patients with severe asthma, it may be suggested that treatment for OSAS can reduce the number of exacerbations, improve the quality of life, and decline the number of obstinate asthma cases. It is very important for general practitioners to assess risk factors, such as body weight, nasal stuffiness, and GERD, and to utilize screening tools for more efficient use of healthcare resources. Considering the known positive effects of CPAP therapy in short-term studies, future investigations should focus on the impact of CPAP therapy on asthma symptoms in the long-term, as well as on the effects of asthma drugs on the course of OSAS.

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A farmacoeconomia e o tratamento da asma

Cited by 2 publications

References 2 publications

Obstructive sleep apnea and asthma

Obstructive sleep apnea and asthma

The problem of obstructive sleep apnea syndrome in asthmatic patients

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