Adenoma alveolar

Saito, Eduardo Haruo; Aaraujo, Luciana Ribeiro de; Carneiro, Leonardo Hoehl; Neto, Antonio Ambrosio de Oliveira; Corrêa, João Carlos Ferrari; Teixeira, Luiz Sérgio Carvalho

doi:10.1590/s1806-37132006000300014

J. bras. pneumol.

2006

DOI: 10.1590/s1806-37132006000300014

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Adenoma alveolar

Eduardo Haruo Saito

Luciana Ribeiro de Aaraujo

Leonardo Hoehl Carneiro

et al.

Abstract: Alveolar adenoma is a rare benign neoplasm of the lungs, and very few cases have been described in the literature. Patients with alveolar adenoma are frequently asymptomatic and are diagnosed through the accidental discovery of a singular, well-delineated nodule on a routine chest X-ray. The definitive diagnosis is made histologically, and the treatment consists of surgical resection of the nodule..

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Cited by 3 publications

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Alveolar adenoma combined with multifocal cysts: Case report and literature review

Wang

Yan

et al. 2013

J Int Med Res

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Alveolar adenoma is an extremely rare and benign pulmonary neoplasm; it is always asymptomatic and is usually detected incidentally on routine chest X-radiography. Typically on imaging examinations, alveolar adenoma exhibits as a peripheral, solitary, cystic nodule in the lung, which may easily imitate other lung lesions, consequently leading to difficulties in the differential diagnosis of this condition. Surgical resection is the primary treatment option. The diagnosis of alveolar adenoma is mainly based on postoperative histopathology, with features of proliferative type 2 alveolar epithelial cells and septal mesenchyme. The present case was a 60-year-old woman with alveolar adenoma, combined with systemic mutifocal cystic lesions. She underwent surgery following the obvious enlargement of this mass and a cystic nodule 7 cm in maximum diameter was resected. Postoperative histopathology confirmed a diagnosis of alveolar adenoma; her prognosis was favourable. In addition to reporting a rare case of alveolar adenoma coexisting with multifocal cysts, the English-language literature was reviewed for similar cases of alveolar adenoma.

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Alveolar adenoma combined with multifocal cysts: Case report and literature review

Wang

Yan

et al. 2013

J Int Med Res

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Alveolar adenoma and coexisting atypical adenomatous hyperplasia: a case report and literature review

Chang

Yeh

et al. 2022

Pathologica

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Summary Alveolar adenoma is a rare tumour of the lung. It is typically found in asymptomatic adults as a peripheral or subplerual nodule on imaging examination. Microscopically, the tumour is composed of admixture of epithelial and mesenchymal component in variable sized cystic or alveolar structures. The tumour shows a benign nature. There have been no reported recurrences or metastases. Malignant transformation of alveolar adenoma and coexisting with lung carcinoma have been rarely described. In this article, we report a case of an alveolar adenoma and coexisting atypical adenomatous hyperplasia. This case, contributing to the limited numbers of cases described to date, illustrates the importance of awareness on the possibility of alveolar adenoma being associated with lung carcinoma and its precursor lesions especially when diagnosed by small biopsy specimens.

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Coexistence of lung alveolar adenoma with cerebral arteriovenous malformations: A case report and literature review

Tang

Shen

2015

Oncology Letters

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Abstract. Alveolar adenoma is an extremely rare benign tumor of the lung derived from type II pneumocytes. To date, only a limited number of alveolar adenoma cases have been reported in the literature. These tumors are usually discovered incidentally on radiographic images. However, other tumor types must be excluded when the characteristics of alveolar adenoma are not typical on the radiographic images. Therefore, diagnosis of alveolar adenomas is based on the combination of gross structural analysis and immunohistochemistry. The present study described a case of alveolar adenoma in a 47-year-old female patient. A chest X-ray revealed a pulmonary lesion in the right lower lobe and, subsequently, the patient underwent a right lower lobectomy. Pathological examination of the surgically resected tissue confirmed the initial diagnosis of alveolar adenoma. In addition, intracranial vascular malformations were detected on a computed tomography scan, but the patient did not experience any notable symptoms. Considering the benign nature of the malformations, as determined by digital subtraction angiography, the patient selected to undergo follow-up with observation only. The postoperative course was uneventful and no recurrence of pulmonary lesions was noted after >4 years, while the condition of the intracranial lesion was stable. In conclusion, the current study described a unique case of adenoma alveolar coexisting with intracranial vascular malformations. A literature review of previously-reported alveolar adenoma cases was also conducted.

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Adenoma alveolar

Cited by 3 publications

References 7 publications

Alveolar adenoma combined with multifocal cysts: Case report and literature review

Alveolar adenoma combined with multifocal cysts: Case report and literature review

Alveolar adenoma and coexisting atypical adenomatous hyperplasia: a case report and literature review

Coexistence of lung alveolar adenoma with cerebral arteriovenous malformations: A case report and literature review

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