Incidência de infecção viral do trato respiratório em asma aguda atendida em sala de emergência

Rocha, Ivete Terezinha Machado da; Menegotto, Diego Milan; Hoffmann, Cristiane Feliciati; Menna-Barreto, Sérgio Saldanha; Dalcin, Paulo de Tarso Roth; Straliotto, Selir Maria; Kang, Suzie Hyona; Pasin, Lilian Rech; Fischer, Josiane; Nieto, Fabiane

doi:10.1590/s1806-37132005000500005

Cited by 1 publication

(6 citation statements)

References 16 publications

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“…Second, it is also important to note that this investigation was performed in a group of hospitalized patients, which is a bias toward the most severe disease cases. Additionally, we do not have the concentrations of individual air pollutants, but it is implausible to reliably separate the effects of air pollutants because they frequently react with each other, sometimes potentiating individual effects . The short study period should also be considered a limitation.…”

Section: Discussionmentioning

confidence: 99%

“…The short study period should also be considered a limitation. Finally, the use of molecular techniques (PCR) in all study patients could be useful, increasing the number of viruses detected, as limited sensitivity of IFI method is well known . Despite these limitations, this is the first study, to our knowledge, to analyze the relationship between RV, meteorological parameters, and air pollution in an adult population.…”

Section: Discussionmentioning

confidence: 99%

“…Sample size requirements were estimated from the literature review. 10 , 11 Using a prevalence of RVI in adults of 15%, with a significance level of 99%, and total confidence interval amplitude of 0·10, we calculated that 339 patients would be needed in the second part of the study.…”

Section: Methodsmentioning

confidence: 99%

“… 9 In adults with acute asthma admitted to the ER, a prevalence of 12·2% of RVI was found. 10 In another study, with adults admitted to hospital with respiratory symptoms, viruses accounted for 15% of hospital admissions for respiratory infections. 11 …”

Section: Introductionmentioning

confidence: 98%

“…In a study with 510 adults hospitalized with pulmonary diseases, an overall prevalence of respiratory viruses (RVs) in the lower respiratory tract was of 42·2%, with rhinoviruses and influenza A virus being the most common . In adults with acute asthma admitted to the ER, a prevalence of 12·2% of RVI was found . In another study, with adults admitted to hospital with respiratory symptoms, viruses accounted for 15% of hospital admissions for respiratory infections …”

Section: Introductionmentioning

confidence: 99%

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Respiratory viral infections and effects of meteorological parameters and air pollution in adults with respiratory symptoms admitted to the emergency room

Silva

Viana

Müller

et al. 2013

Influenza Resp Viruses

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BackgroundRespiratory viral infections (RVIs) are the most common causes of respiratory infections. The prevalence of respiratory viruses in adults is underestimated. Meteorological variations and air pollution are likely to play a role in these infections.ObjectivesThe objectives of this study were to determine the number of emergency visits for influenza-like illness (ILI) and severe acute respiratory infection (SARI) and to evaluate the association between ILI/SARI, RVI prevalence, and meteorological factors/air pollution, in the city of Porto Alegre, Brazil, from November 2008 to October 2010.MethodsEleven thousand nine hundred and fifty-three hospitalizations (adults and children) for respiratory symptoms were correlated with meteorological parameters and air pollutants. In a subset of adults, nasopharyngeal aspirates were collected and analyzed through IFI test. The data were analyzed using time-series analysis.ResultsInfluenza-like illness and SARI were diagnosed in 3698 (30·9%) and 2063 (17·7%) patients, respectively. Thirty-seven (9·0%) samples were positive by IFI and 93 of 410 (22·7%) were IFI and/or PCR positive. In a multivariate logistic regression model, IFI positivity was statistically associated with absolute humidity, use of air conditioning, and presence of mold in home. Sunshine duration was significantly associated with the frequency of ILI cases. For SARI cases, the variables mean temperature, sunshine duration, relative humidity, and mean concentration of pollutants were singnificant.ConclusionsAt least 22% of infections in adult patients admitted to ER with respiratory complaints were caused by RVI. The correlations among meteorological variables, air pollution, ILI/SARI cases, and respiratory viruses demonstrated the relevance of climate factors as significant underlying contributors to the prevalence of RVI.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%