Atypical hepatic hemangioma: imaging features of hyalinized hemangioma

Nunes, Letícia Maria Araujo Oliveira; Mello-Amoedo, Caroline Duarte de; Yamauchi, Fernando Ide; Baroni, Ronaldo Hueb

doi:10.1590/s1679-45082018ai4256

Cited by 1 publication

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“…Tissue was obtained at autopsy in 5 cases, surgical resection specimen in 37 cases and liver biopsy in 13 cases. Only two cases were proofed radiological to be HSH on regular follow up [12,13]. In the present cases, liver core biopsy was obtained and assessed by two independent liver pathologists.…”

Section: Discussionmentioning

confidence: 91%

Hepatic sclerosing hemangioma mimics hepatic malignancies: a case report and multidisciplinary approach

Sweed

Fayed

Sweed

et al. 2019

Egypt Liver Journal

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Background: Hepatic sclerosing hemangiomas (HSH) are rare benign vascular tumors that mimic radiologically hepatic malignancies. HSH is characterized by extensive fibrosis and hyalinosis as a result of degeneration and thrombosis. Pre-operative diagnosis is very difficult and most of the cases undergo surgical resections. Case presentation: A 65 years old, hepatitis C virus-infected female presented by an accidentally discovered hepatic focal lesion. Magnetic resonance imaging (MRI) showed a T2 hyperintense mass displaying peripheral enhancement in porto-venous phase. The patient had a simultaneous typical hepatic hemangioma and multiple vertebral bodies' hemangiomata. Tissue-guided biopsy revealed a densely sclerotic stroma containing vascular spaces with occasional obliteration of the lumen. Immunohistochemical staining was performed for Pan CK, CD34, SMA, VEGF, and c-Kit which confirmed the vascular nature of neoplasm and the involuting phase of hemangioma development. The patient was reassured and recommended for a regular radiological follow-up to reassess the lesion size. Conclusion: The definitive preoperative diagnosis of HSH is still problematic. However, the awareness of surgeons by this entity, peripheral enhancement in porto-venous phase on dynamic MRI, the presence of simultaneous typical hepatic hemangioma in the absence of cancer history could raise suspicion for HSH. Liver biopsy is still the gold standard in approaching the accurate diagnosis.

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Section: Discussionmentioning

confidence: 91%