SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient
Maria Cassia Mendes-Correa,
Fábio de Rose Ghilardi,
Matias Chiarastelli Salomão
et al.
Abstract:This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-cell lymphoma. He developed a persistent SARS-CoV-2 infection lasting at least 218 days and did not manifest a humoral immune response to the virus during this follow-up period. Whole-genome sequencing and viral cultures confirmed a persistent infection with a replication-posit… Show more
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