Relevance of epidemiological surveillance in travelers: an imported case of Leishmania tropica in Mexico

Fernández-Figueroa, Edith A.; Sánchez‐Montes, Sokani; Miranda-Ortíz, Haydee; Mendoza-Vargas, Alfredo; Cervantes-Sarabia, Rocely; Cárdenas-Ovando, Roberto A.; Ruiz‐Remigio, Adriana; Becker, Ingeborg

doi:10.1590/s1678-9946202062041

Cited by 3 publications

(3 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, tracking the presence of exotic species, e.g. L. tropica discovered in a returned traveller to Mexico, allows local health authorities to enact sanitary measures (such as indoor residual spraying) [ 42 ]. Consequently, a globally applicable technique that captures both genus- and species-level data has been suggested, to mitigate assay design complications, such as intraspecies heterogeneity and gene target copy number variations, and to detect asymptomatic and multiple-organism infections (including co-infection with multiple Leishmania species) [ 6 ].…”

Section: The Importance Of the Detection And Identification Of ...mentioning

confidence: 99%

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

et al. 2022

View full text Add to dashboard Cite

Leishmania infections span a range of clinical syndromes and impact humans from many geographic foci, but primarily the world’s poorest regions. Transmitted by the bite of a female sand fly, Leishmania infections are increasing with human movement (due to international travel and war) as well as with shifts in vector habitat (due to climate change). Accurate diagnosis of the 20 or so species of Leishmania that infect humans can lead to the successful treatment of infections and, importantly, their prevention through modelling and intervention programs. A multitude of laboratory techniques for the detection of Leishmania have been developed over the past few decades, and although many have drawbacks, several of them show promise, particularly molecular methods like polymerase chain reaction. This review provides an overview of the methods available to diagnostic laboratories, from traditional techniques to the now-preferred molecular techniques, with an emphasis on polymerase chain reaction-based detection and typing methods. Graphical abstract

show abstract

Section: The Importance Of the Detection And Identification Of ...mentioning

confidence: 99%

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Management strategy was described in 506 patients (Table 6): 282 (55.7%) received systemic treatment, 172 (34.0%) local treatment, 4 (0.8%) combined local and systemic treatment and 48 (9.5%) no treatment. A total of 65 failures or relapses were reported, representing 12.8% of cases [30,69,83,85,86,95,112,115,123,132,134,135,145,152,153,164,176,180,227,235,238,244]. When retreatment was described (n = 28, [30,83,85,86,112,115,123,134,135,145,152,164,176,180,227,235,238,244]), it most often consisted of a different strategy and/or drug (93.1%, [83,85,86,112,115,123,…”

Section: Clinical Aspects and Management Of Cutaneous Leishmaniasismentioning

confidence: 99%

“…A total of 65 failures or relapses were reported, representing 12.8% of cases [30,69,83,85,86,95,112,115,123,132,134,135,145,152,153,164,176,180,227,235,238,244]. When retreatment was described (n = 28, [30,83,85,86,112,115,123,134,135,145,152,164,176,180,227,235,238,244]), it most often consisted of a different strategy and/or drug (93.1%, [83,85,86,112,115,123,132,134,135,145,…”

Section: Clinical Aspects and Management Of Cutaneous Leishmaniasismentioning

confidence: 99%

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

Rocha¹,

Pereira

Maia³

2022

Pathogens

View full text Add to dashboard Cite

Leishmaniases are human and animal parasitic diseases transmitted by phlebotomine sand flies. Globalization is an important driver of the burden and in the current dynamics of these diseases. A systematic review of articles published between 2000 and 2021 was conducted using the PubMed search engine to identify the epidemiology and clinical management of imported human leishmaniases as a fundamental step to better manage individual cases and traveler and migrant health from a global perspective. A total of 275 articles were selected, representing 10,341 human imported cases. Identified drivers of changing patterns in epidemiology include conflict and war, as well as host factors, such as immunosuppression, natural and iatrogenic. Leishmania species diversity associated with different clinical presentations implies diagnostic and treatment strategies often complex to select and apply, especially in non-endemic settings. Thus, diagnostic and management algorithms for medical clinical decision support are proposed. Increased surveillance of non-endemic cases, whether in vulnerable populations such as refugees/migrants and immunocompromised individuals or travelers, could improve individual health and mitigate the public health risk of introducing Leishmania species into new areas.

show abstract

Molecular evidence of Leishmania spp. in spider monkeys (Ateles geoffroyi) from The Tuxtlas Biosphere Reserve, Veracruz, Mexico

et al. 2021

View full text Add to dashboard Cite

Relevance of epidemiological surveillance in travelers: an imported case of Leishmania tropica in Mexico

Abstract: This is an open-access article distributed under the terms of the Creative Commons Attribution License.

Cited by 3 publications

References 19 publications

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

Molecular evidence of Leishmania spp. in spider monkeys (Ateles geoffroyi) from The Tuxtlas Biosphere Reserve, Veracruz, Mexico

Contact Info

Product

Resources

About