Oral Candida spp. colonization in human immunodeficiency virus-infected individuals

Moris, Daniela Vanessa; Melhem, M. S. C.; Martins, Marilena dos Anjos; Mendes, Rinaldo Pôncio

doi:10.1590/s1678-91992008000200004

Cited by 19 publications

(19 citation statements)

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“…in the oral cavity was also found in a group of children of a school from different socioeconomic status without candidiasis lesions, in which C. albicanswas the prevailing specie, corresponding to 95% of all the isolates (Moreira et al, 2001). Yeasts of Candida play an extremely important role in high frequent infections and colonization in humans (Moris et al, 2008;Lass-Flörl, 2009;Savastano et al, 2016). These findings agrees with the reported by several authors related to the colonization prevalence of C. albicans over other species in the oral cavity, and consequently on the subsequent candidiasis development (Moreira et al, 2001;Grimoud et al, 2003;Naglik et al, 2003;Moris et al, 2008;Moyes and Naglik, 2011).…”

Section: Discussionsupporting

confidence: 90%

“…The most frequent isolated specie was again C. albicans, found in 51.4% of the patients. C. albicansis without a doubt the most frequently isolated specie in both superficial and invasive infections from different anatomic sites, and the most common cause of candidiasis and candidemia worldwide (Moris et al, 2008;Hinrichsen et al, 2009;Savastano et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…on human skin and mucosa, facilitates the occurrence of oral or systemic candidiasis (Moris et al, 2008). The virulence factors of the fungus and the immune status of the individual are two parameters which controls the onset of Candida spp.…”

Section: Discussionmentioning

confidence: 99%

“…Some authors have stated that hospitalized patients tend to develop a higher oral candidiasis prevalence, due to both local and systemic alterations, changing the microbiota and contributing to this kind of infections (Grimoud et al, 2003;Meurman and Hamalainen, 2006;Moris et al, 2008). In addition, many intrinsic and extrinsic factors influence the composition, metabolic activity and pathogenicity of a variety of microorganisms in the oral cavity (Bodineau et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

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Exogenous niacin treatment increases NADPH oxidase in kiwifruit

et al. 2018

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The aim of this study was to evaluate the frequency of Candida species between a non-hospitalized and a hospitalized population. For this purpose, samples of saliva were sampled through sterile swabs, moistened in peptone water and rubbed in the oral cavity of 140 individuals, from which, 70 were hospitalized patients from the Medical Clinic of a Teaching Hospital and the other 70 were non-hospitalized subjects. All saliva samples were plated in Sabouraud Dextrose agar added with Chloramphenicol and incubated at 36 °C for 48 hours. The morphology identification was performed through macroscopic and microscopic characterization, the CHROMagar Candida medium and the VITEK  system Yeast Biochemical Card (bio Mérieux SA, France). The results showed a colonization of Candida spp. in 85.7% the hospitalized individuals, where the species found were C. albicans (60%), C. tropicalis (23.4%), C. krusei (3.3%) and Candida spp. (13.3%). In the non-hospitalized individuals the colonization by Candida spp was 47.1%, and the species found were: C. albicans (45.5%), C.krusei (9.1%), C. guilliermondii (9.1% %), C. tropicalis (3.0%), C. famata (3.0%) and Candida spp. (30.3%). In spite of their presence in oral cavity in both groups, Candida spp. was more frequently isolated in hospitalized individuals, who were 6.73 times more likely to have this fungus in the oral cavity and were 3.88 times more likely to have Candida albicans. Nos indivíduos não-hospitalizados a colonização por Candida spp foi de 47,1%, e as espécies encontradas foram: C. albicans (45,5%), C. krusei (9,1%), C. guilliermondii (9,1%), C. tropicalis (3,0%), C. famata (3,0%) e Candida spp. (30,3%). Apesar de sua presença na cavidade oral em ambos os grupos, Candida spp. foi mais freqüentemente isolada em indivíduos hospitalizados, que foram 6,73 vezes mais propensos a ter este fungo na cavidade oral e foram 3,88 vezes mais propensos a ter Candida albicans. KeywordsPalavras-chave: Candida spp. oral, colonização, pacientes hosptalizados, infecções hospitalares.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Exogenous niacin treatment increases NADPH oxidase in kiwifruit

et al. 2018

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“…Recently more and more non-albicans Candida species are isolated from oral and cervical smears of HIV patients and this is a matter of high concern as non albicans species is thought to be mainly due to advanced immunosuppression or resistant to antifungal therapy and are supposed to be invasive forms of Candidiasis. [1,5,6] India had about 2.1 million people living with HIV at the end of 2016. This is one of the most studied dreadful disease.…”

Section: Vaginal Candidal Colonizationmentioning

confidence: 99%

Comparison of Candidal Species in Oral and Cervical Smears in Human Immunodeficiency Virus Positive Women- A Prospective Study

Jahagirdar¹,

Kumar²,

Suneetha³

et al. 2017

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Background: Mucosal candidiasis which includes oropharyngeal and vaginal candidiasis, is suggested to be an early sign in immunocompromised individuals especially in HIV positive patients Aims and Objectives: To compare the frequencies of oropharyngeal and vaginal candidal colonization among HIV-seropositive women. Methods: We carried our study in 70 HIV positive women. A detailed medical history was taken. The variables recorded were age, educational status, antibiotics usage, occupation, marital status and usage of contraceptives. Oral and cervical smears were taken and cultured on Sabouraud dextrose agar and HiCrome agar, and candidal colonies were counted. Statistical analysis was performed with SPSS for Windows: IBM Corp. Version 20.0. Armonk, NY, USA. Results: Oropharyngeal candidal colonization was seen in 42 (60%) women. Candida albicans was most commonly identified (90%), followed by C tropicalis (5%) and C glabrata (3%). Vaginal colonization was identified in 38 (54%) women. C. albicans was most commonly identified (80%), followed by C. glabrata (15%) and C. tropicalis (3%). Conclusion: There were more non albicans species in vaginal smears than oral smears, suggesting dissimilar pathogenesis in both the sites.

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Yeasts isolated from Algerian infants’s feces revealed a burden of Candida albicans species, non-albicans Candida species and Saccharomyces cerevisiae

et al. 2015

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This study aimed at showing the yeast diversity in feces of Algerian infants, aged between 1 and 24 months, hospitalized at Bejaia hospital (northeast side of the country). Thus, 20 colonies with yeast characteristics were isolated and identified using biochemical (ID32C Api system) and molecular (sequencing of ITS1-5.8S-ITS2 region) methods. Almost all colonies isolated (19 strains) were identified as Candida spp., with predominance of Candida albicans species, and one strain was identified as Saccharomyces cerevisiae. Screening of strains with inhibitory activities unveiled the potential of Candida parapsilosis P48L1 and Candida albicans P51L1 to inhibit the growth of Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923. Further studies performed with these two Candida strains revealed their susceptibility to clinically used antifungal compounds and were then characterized for their cytotoxicity and hemolytic properties. On the other hand, Saccharomyces cerevisiae P9L1 isolated as well in this study was shown to be devoid of antagonism but resulted safe and overall usable as probiotic.

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Oral Candida spp. colonization in human immunodeficiency virus-infected individuals

Cited by 19 publications

References 100 publications

Exogenous niacin treatment increases NADPH oxidase in kiwifruit

Exogenous niacin treatment increases NADPH oxidase in kiwifruit

Comparison of Candidal Species in Oral and Cervical Smears in Human Immunodeficiency Virus Positive Women- A Prospective Study

Yeasts isolated from Algerian infants’s feces revealed a burden of Candida albicans species, non-albicans Candida species and Saccharomyces cerevisiae

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