Abstract:The complement system, an important effector mechanism of innate immunity can be activated by three distinct mechanisms designated classical, alternative and lectin pathways. The functional activity of complement can be assessed by hemolytic assays that are valuable screening tools for complement component deficiencies. The aim of this study was to evaluate the alternative complement pathway in normal canine serum samples using the hemolytic assay (AH50). First the canine alternative pathway activation by eryt… Show more
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