Oral Surgery

Abstract

The animals were sacrificed 3, 7, 20 and 30 days after the implantation procedure and the specimens were prepared for histological evaluation. The results showed that Papacárie ® caused a moderate inflammatory response up to the 20th day, which decreased at 30 days. The gel base showed a discrete inflammation, which increased at 30 days. Papacárie ® and its gel base were proved biocompatible with the connective tissue, although the alterations caused for these materials were statistically different (Mann Whitney; p< 0,05).