Video-assisted left inguinal lymphadenectomy for penile cancer

Britto, Cesar; Rebouças, Rafael B; Lopes, Tassilo Rodrigo Araujo; Costa, Thiago Silva Da; Leite, Rodrigo de Carvalho Holanda; Carvalho, Pedro Sales Lima de

doi:10.1590/s1677-55382012000200020

Cited by 10 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As surgeons’ experience increases in laparoscopic surgeries, it is natural for their indications to expand. Video-endoscopic inguinal lymphadenectomy [16] allows the surgeon to familiarize himself with the thigh approach and thus getting a safe feeling when performing new procedures, such as gracilis mobilization.…”

Section: Discussionmentioning

confidence: 99%

Video-Endoscopic Mobilization of the Gracilis Muscle for Rectourinary Fistula Repair

Britto

Pfalzgraf

Lima³

et al. 2021

Urol Int

View full text Add to dashboard Cite

Introduction: Transposition of the gracilis has been used in a large number of reconstructive procedures. Its advantage is its proximity to these defects and a good blood supply. Traditionally, the gracilis mobilization is performed by open surgery with one or more incisions. We describe our initial experience with the video-endoscopic mobilization of gracilis. Method: We described a retrospective review of all patients who underwent gracilis muscle mobilization for treatment of rectourethral fistula, performed by video-endoscopy, between March 2013 and September 2017, for treatment of rectourethral fistula. Also, our surgical technique is described in detail. Results: Three patients, with a mean age of 66.6 years, underwent the procedures. The mean time for mobilization of the gracilis was 107 min (range 60–145). There was no case of donor area infection, no change in the sensitivity of the medial aspect of the thigh or chronic pain. Conversion to open surgery was not necessary in any case. The hospital discharge occurred in average after 4 days. The bladder catheter was removed after 4 weeks after cystography was performed without evidence of leakage. One patient had a recurrence of the fistula. Discussion: The gracilis is an excellent choice of tissue to be interposed in reconstructive procedures of the perineal region, especially in the treatment of rectourinary fistulas. However, endoscopic harvest of the gracilis muscle has not yet found its way into everyday practice. The results in the treatment of rectourinary fistulas are excellent, with a success rate of 87.7%. Our rate of 67% is below, probably due to the small number of cases. In open surgery, complications are uncommon; however, approximately half of the patients expressed concern about the painful scar, which can be reduced by minimally invasive access. Conclusion: Video-endoscopic mobilization of gracilis muscle for the treatment of rectourethral fistula is feasible and safe. Studies comparing this technique with the conventional mobilization are required.

show abstract

Section: Discussionmentioning

confidence: 99%

Video-Endoscopic Mobilization of the Gracilis Muscle for Rectourinary Fistula Repair

Britto

Pfalzgraf

Lima³

et al. 2021

Urol Int

View full text Add to dashboard Cite

show abstract

“…However, these surgical techniques are limited by their high rates of morbidity and mortality [47]. Recent studies have shown new surgical techniques that have improved patient survival [48,49]. …”

Section: Histopathological Data: Involvement Of Lymph Nodes As Thementioning

confidence: 99%

Epigenetic Mechanisms in Penile Carcinoma

Kuasne

Marchi²,

Rogatto

et al. 2013

IJMS

View full text Add to dashboard Cite

Penile carcinoma (PeCa) represents an important public health problem in poor and developing countries. Despite its unpredictable behavior and aggressive treatment, there have only been a few reports regarding its molecular data, especially epigenetic mechanisms. The functional diversity in different cell types is acquired by chromatin modifications, which are established by epigenetic regulatory mechanisms involving DNA methylation, histone acetylation, and miRNAs. Recent evidence indicates that the dysregulation in these processes can result in the development of several diseases, including cancer. Epigenetic alterations, such as the methylation of CpGs islands, may reveal candidates for the development of specific markers for cancer detection, diagnosis and prognosis. There are a few reports on the epigenetic alterations in PeCa, and most of these studies have only focused on alterations in specific genes in a limited number of cases. This review aims to provide an overview of the current knowledge of the epigenetic alterations in PeCa and the promising results in this field. The identification of epigenetically altered genes in PeCa is an important step in understanding the mechanisms involved in this unexplored disease.

show abstract

“…In the past 18 months, two new centers adopted and presented their results for laparoscopic and robotic inguinal LND. Britto et al [97] reported laparoscopic bilateral inguinal lymphadenectomy yielding 31 lymph nodes without perioperative complications, whereas Dogra et al [98] reported robotic bilateral inguinal LND (Fig. 3 [98]) in two patients discharged home in 48 h without complication.…”

Section: Penile Cancermentioning

confidence: 99%