Invasive bladder cancer in the eighties: transurethral resection or cystectomy?

Faba, Ó. Rodríguez; Palou, Joan; Urdaneta, Guillermo; Gausa, L.; Villavicencio, H.

doi:10.1590/s1677-55382011000100007

Cited by 4 publications

(1 citation statement)

References 21 publications

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“…Regardless, when comparing TURBT to RC in elderly patients, TURBT alone had a much worse cancer specific and overall survival [87]. Other retrospective series evaluating bladder preservation strategies have also shown worse cancer specific outcomes for elderly patients with MIBC compared to RC series [88,89].…”

Section: Bladder Sparing Protocolsmentioning

confidence: 99%

Optimal Management of the Elderly Patient with Muscle-Invasive Bladder Cancer

Pietzak

Drach

Malkowicz

et al. 2013

Curr Transl Geriatr Exp Gerontol Rep

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With the growing elderly demographic and the peak incidence of bladder cancer being approximately 70 years old, an increasing number of elderly patients will develop invasive bladder cancer. Several studies suggest that a survival gap exists between elderly patients with invasive bladder cancer and younger cohorts. Radical cystectomy is the standard of care that provides good cancer-specific survival, but few elderly patients are referred for cystectomy. This is likely, at least in part, due to concern with the morbidity associated with the operation. Cisplatin is the most effective chemotherapeutic agent used to treat invasive bladder cancer but some patients cannot receive it due to toxicity. There are few promising alternatives to cisplatin at this time. This review discusses opportunities for improved care, recent therapeutic advances, and future directions to improve the outcome for elderly patients with invasive bladder cancer. Keywords Muscle invasive bladder cancer. Elderly. Radical cystectomy. Cisplatin. Cisplatin unfit. Urinary diversion. Bladder sparing. Bladder cancer. Urothelial carcinoma. Radical TURBT Radical Cystectomy in the Elderly: An Under-Utilized Standard of Care Radical cystectomy with urinary diversion (RC) offers the best chance of survival for patients with MIBC and remains E. J.

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Section: Bladder Sparing Protocolsmentioning

confidence: 99%