Epidemiologic characteristics of renal cell carcinoma in Brazil

Abstract

Purpose: In Brazil, National data regarding the epidemiology of renal cell carcinoma (RCC) are scarce. The aim of this study was to describe the demographic, clinical, and pathologic characteristics of RCC diagnosed and treated by members of the SBU -Brazilian Society of Urology. Results: Fifty SBU affiliated institutions contributed with patient information to the study. Of the 508 patients, 58.9% were male, 78.9% were white, and the mean age was 59.8 years. Smoking history, high blood pressure and a body mass index above 30 kg/m 2 were present in 14.8%, 46.1% and 17.9% of the patients, respectively. Abdominal ultrasound and computed tomography were the main diagnostic methods. The majority of the cases were localized tumors and metastasis were presented in 9.5% of the patients; 98.4% underwent nephrectomy. Clear cell carcinoma was the most common histological type. In comparison with private institutions, stage IV disease was less frequent among patients treated at public health services (P = 0.033). Conclusions: RCC in Brazil is more common in white men in their sixth decade of life. Ultrasound is the main diagnostic tool for the diagnosis of clear cell carcinoma and we found that localized disease was predominant. A national registry of RCC is feasible and may provide valuable information.

Comparison of the epidemiologic features and patterns of initial care for prostate cancer between public and private institutions: a survey by the Brazilian Society of Urology

“…The results presented herein confirm that statewide registry of prostate cancer is feasible and provides valuable information regarding patient demographics, clinical features, and patterns of care, analogously to national studies previously conducted by SBU in other disease settings (28,29). The results of this study suggest that significant disparities exist for patients with prostate cancer attended at public and private institutions, but the relative contribution of biological versus socioeconomic features remains uncertain at present.…”

Prognostic factors in renal cell carcinoma: analysis of 227 patients treated at the Brazilian National Cancer Institute

“…The Brazilian Society of Urology, through the ENCARE study, initiated a project aimed to carry out an epidemiological study of renal cancer in our country. Recently complete data from this study was published (4). The current work aims to show, from a survey of factors relevant to disease, the profile of patients with this type of pathology at the National Cancer Institute over the past six years.…”

Estudo de candidatos a biomarcadores moleculares de prognóstico em carcinoma renal de células claras

“…O CCR é o sétimo câncer mais comum entre os pacientes de sexo masculino e o nono entre as mulheres, estimando-se uma incidência mundial de aproximadamente 209 mil novos casos de CCR por ano, ocasionando 102 mil mortes (EBLE et al, 2004;RINI et al, 2009). No Brasil, esta doença não se encontra entre os 10 tipos de câncer mais prevalentes e os dados epidemiológicos relativos ao CCR são escassos (INSTITUTO NACIONAL DO CÂNCER, 2011;NARDI et al, 2010). Registros regionais apresentam uma prevalência da doença de aproximadamente 1,2%, com 2.760 casos novos somente na cidade de São Paulo (INSTITUTO NACIONAL DO CÂNCER, 2010;NARDI et al, 2010).…”

“…No Brasil, esta doença não se encontra entre os 10 tipos de câncer mais prevalentes e os dados epidemiológicos relativos ao CCR são escassos (INSTITUTO NACIONAL DO CÂNCER, 2011;NARDI et al, 2010). Registros regionais apresentam uma prevalência da doença de aproximadamente 1,2%, com 2.760 casos novos somente na cidade de São Paulo (INSTITUTO NACIONAL DO CÂNCER, 2010;NARDI et al, 2010). Embora a incidência seja baixa, a maior preocupação reside em que o prognóstico dos pacientes é diretamente relacionado ao estadio em que a doença é diagnosticada.…”

“…Dos restantes, 30 a 50% dos pacientes irão desenvolver metástase no curso da doença, com uma taxa de sobrevida de até 10% em cinco anos (BANKS et al, 2007;LANE, 2013). Diferente dos dados mundiais, no Brasil a incidência de pacientes que apresentaram metástase ao diagnóstico foi de 9,5% (NARDI et al, 2010).…”