Abstract:Purpose: Little data are available on radical prostatectomy findings in men who experience disease progression following active surveillance. Materials and Methods: A total of 470 men in our active surveillance program underwent annual repeat needle biopsies to look for progression defined as any Gleason pattern grade 4/5, more than 50% cancer on any core or cancer in more than 2 cores. Slides were available for review in 48 of 51 radical prostatectomies with progression. Results: The average time between the … Show more
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