Deep-seated sarcomas of the penis

Abstract

Mesenchymal neoplasias represent 5% of tumors affecting the penis. Due to the rarity of such tumors, there is no agreement concerning the best method for staging and managing these patients. Sarcomas of the penis can be classified as deep-seated if they derive from the structures forming the spongy body and the cavernous bodies. Superficial lesions are usually low-grade and show a small tendency towards distant metastasis. In contrast, deep-seated lesions usually show behavior that is more aggressive and have poorer prognosis. The authors report 3 cases of deep-seated primary sarcomas of the penis and review the literature on this rare and aggressive neoplasia.

Dermatofibrosarcoma protuberans of penis: Case report and literature review

“…[19] Penile sarcoma is usually treated by total penectomy with or without associated radiation and chemotherapy. [20] Regardless of the therapeutic modality used, the majority of patients die in less than two years due to systemic dissemination. [20] While only one case of DFSP has been reported so far, DFSP has got less chances of local and distant metastasis than sarcoma, and treatment is local resection as contrary to sarcoma, which may need total penectomy.…”

Non-squamous cell carcinoma of the penis: single-center, 15-year experience

“…As noted in the MSKCC series, the strongest predictors of outcome were tumor depth and size. The vascular tissue of the corporal bodies is likely the source of deep-seated tumors, which contributes to the aggressive behavior and poorer prognosis of these tumors and thus mandates complete resection of the tumor [20, 21]. Sarcoma patients typically have local recurrence and/or distant metastasis, and lymphatic metastasis is not commonly noted with genitourinary sarcomas; thus, inguinal lymphadenectomy is generally unnecessary in nonpalpable disease [4, 22].…”

Color Doppler US of the Penis

“…Large lesions present with inhomogeneous signal intensity and enhancement characteristics (Antunes et al 2005). Urethral carcinoma and sarcomas are usually hypointense or isointense relative to the corpora on T1-weighted images and hypointense or heterogeneous on T2weighted images .…”