Reconstructive urology

Abstract

greatly facilitate future clinical studies in terms of consistency of vaccine administered and the provision of primed DCs for in vitro assessment of response. Editorial CommentThis is a very well done scientific research with immediate potential clinical implications. As the authors stated, one of the most significant limitation to current dendritic cell-based immunotherapy is the need to prepare fresh vaccine repeatedly. The ability to culture and cryopreserve numerous aliquots of identical dendritic cells from a single venesection would reduce hospital intervention for patients, and greatly facilitate clinical trials by allowing the manipulation of dendritic cells before or after freezing, and their subsequent use as sequential vaccines.The authors demonstrated the feasibility of a potentially generic approach to cellular immunotherapy, and the preparation of identical aliquots of dendritic cell vaccine that were readily tested for safety and immunoreactivity before injecting into patients. Dendritic cell therapy resulted in significant in vitro immunological responses in patients even with very advanced disease. Also, in this study, dendritic cell vaccine showed to be safe and non-toxic Urol. 2003; 13: 489-94 Purpose of Review: Reconstructive surgery for patients with genital abnormalities or for patients who require reconstructive efforts is challenging. This review highlights those articles, which are outstanding among all those important papers, which have been published during the last year (2002)(2003).Recent Findings: A greater understanding of embryonal development improves the success of reconstructive surgery. Other factors, such as the patient's sex, influence the surgical technique used and the degree of invasiveness or complexity. In the adult the pressure to shorten hospital stays has played a big part in the continual modification and enhancement of surgical techniques. In addition to modified techniques, new off-the-shelf materials are introduced to the clinic, which seem to have the potential to improve the surgical outcome and shorten hospital stays.Summary: With the continued successful basic anatomy and basic research, reconstructive surgery brings higher success rates. Long-term results are still required to validate the reliability of these new surgical techniques and materials. Editorial CommentThis paper nicely outlines the current status of reconstruction of male and female genitalia for a successful reconstruction in genital abnormalities a greater understanding of the embryonal development is advantages. Flap technology and prefabrication are the currently preferred methods for surgical success in transsexual Purpose: Orthotopic urinary diversion is a feasible and optimal technique for many women undergoing cystectomy. Although successful outcomes have been achieved, groups at most centers have strict selection criteria. We evaluated our experience with female orthotopic diversion in traditional and nontraditional candidates.Materials and Methods: From September 1, 1995 to Febru...