Reconstructive urology

Abstract

Conclusions: In this pilot study in a rabbit model the haemostatic effect of fibrin glue was confirmed on covering a defect in the tunica albuginea. Moreover, there was regeneration of normal tunica albuginea with no scarring at 6 weeks and maintained at 12 weeks. Further well-controlled studies are required before using fibrin glue for corporal body grafting to treat chordee. Editorial Comment Many materials have been investigated for corporal body grafting in surgical correction of chordee and Peyronie's disease (porcine small intestinal submucosa and tunica acellular matrix, as examples). This article evaluated the feasibility of using a commercially available fibrin glue ('Tisseel', Baxter Healthcare Corp., Irvine, California) for covering corporal body defects, with potential application in the surgical management of severe chordee. In rabbits, the results were excellent. Fibrin glue may be considered a suitable substance for corporal body grafting in the future.