Adenomatoid tumor of supra-renal gland

Abstract

Adenomatoid tumors of adrenal gland are rare, asymptomatic neoplasias, with benign behavior, and usually are diagnosed incidentally.We report a case of a voluminous adenomatoid tumor of left adrenal gland in a 42-year old man who sought evaluation because of renal colic due to left nephrolithiasis. During the investigation, a tumor localized in left adrenal gland was identified by ultrasonography (14.3 x 10.5 x 19.0).The patient underwent adrenalectomy and pyelolithotomy with histopathological and immunohistochemical diagnosis of adenomatoid tumor of adrenal gland, being the largest one described in the literature to the moment. The patient does not present any signs of recurring lesion after a 3-year follow-up.

Adenomatoid tumor of the adrenal gland: Case report with immunohistochemical study

“…AT of the adrenal gland is extremely rare. This tumor has only recently been recognized, with only 26 cases in the literature to date 8–24 . The clinicopathological features of 27 cases of adrenal AT, including the present case, are as follows.…”

“…The gross finding seemed to be mostly solid and gray to white, sometimes associated with cysts 23 . The tumor was usually found incidentally, but five cases were associated with hypertension even in young patients 9,17 , 18,22 , 23 . Although the relationship between adrenal AT and hypertension is still unclear, adrenal AT might stimulate cortical or medullary tissue of the adrenal gland.…”

“…Although the relationship between adrenal AT and hypertension is still unclear, adrenal AT might stimulate cortical or medullary tissue of the adrenal gland. Of the patients treated with surgical resection, no report demonstrated tumor recurrence or metastasis 22–24 …”

“…Extragenital AT have been reported to occur in the omentum, 1 umbilical skin, 2 the mesentery of the small intestine, 3 pancreas, 4 mediastinal lymph node, 5 pleura, 6 and heart 7 . Adrenal AT have been recently recognized and 26 cases were reported with marked male predominance 8–24 . We herein report an autopsy case of adrenal AT with acute coronary thrombosis resulting in heart failure, and examine the tumor immunohistochemically with reference to sex hormone receptors, and discuss its histogenesis.…”

Adenomatoid Tumor of the Adrenal Gland: Report of Two Cases and Review of the Literature

“…Fan et al (17) reported a case of adrenal AT with a concurrent left kidney cyst and left nephrolithiasis in a man with moderate hypertension. Moreover, two cases of adrenal AT in a man who sought evaluation of renal colic or acute right flank pain due to nephrolithiasis were reported by Denicol et al (13) and Varkarakis et al (15), respectively. A few patients had a history of sarcoma (6), inguinal hernia (18), colon cancer (20), and mucoepidermoid carcinoma (11), and adrenal AT was incidentally discovered.…”