Renal cell carcinoma in childhood

Barros, Luciano R.; Glina, Sidney; Mello, Luiz Figueiredo

doi:10.1590/s1677-55382004000300011

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…No proper therapy has been defined for children with RCC. Surgery constitutes the main treatment and results in cure when the tumor is localized and completely resected [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Pediatric Papillary Renal Cell Carcinoma in a Horseshoe Kidney: A Case Report with Review of the Literature

Loya-Solis¹,

Alemán-Meza

Canales-Martínez

et al. 2015

Case Reports in Pathology

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Renal cell carcinoma is the most common malignancy of the kidney in adults. In children, however, it only accounts for an estimated 1.8 to 6.3% of all pediatric malignant renal tumors. Papillary renal cell carcinoma is the second most common type of renal cell carcinoma in children. We present the case of a 12-year-old boy with a 2-month history of abdominal pain, unexplained weight loss, and gross hematuria. Computed tomography revealed a horseshoe kidney and a well-defined mass of 4 cm arising from the lower pole of the right kidney. Microscopically the tumor was composed of papillae covered with cells with abundant eosinophilic cytoplasm and high-grade nuclei with prominent nucleoli. Immunohistochemistry was performed; EMA, Vimentin, and AMACR were strongly positive while CK7, CD10, RCC antigen, TFE3, HMB-45, and WT-1 were negative. Currently, 10 months after the surgical procedure, the patient remains clinically and radiologically disease-free.

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“…No proper therapy has been defined for children with RCC. Surgery constitutes the main treatment and results in cure when the tumor is localized and completely resected [ 6 ].…”

Section: Introductionmentioning

confidence: 99%