Female urology

Abstract

Results: The overall cancer detection rate was 38% and 51% for 6 and 12 core biopsy, respectively. In patients with PSA between 4.1 and 10 ng/ml the cancer detection rate was 30% and 49% for 6 and 12 core biopsy, respectively.Conclusions: The 12 core transperineal prostate biopsy is superior to 6 core biopsy. The technique provides optimal prostate cancer diagnosis. About half of the patients with PSA greater than 4.0 ng/ml and a slightly lower percent with PSA between 4.1 and 10 ng/ml have prostate cancer. Editorial CommentThe rationale for performing 12 core biopsies in patients with prostate carcinoma is rarely given as clear as it is in the data presented with this paper.Moreover, these data provide an impressive insight into true (?) the incidence of prostate carcinoma in a population with elevated PSA. Overall cancer detection rate was 38% and 51 % for 6 and 12 core biopsies, respectively. In patients with PSA between 4 and 10 ng/ml, the cancer detection rate was 30% and 49% for 6 and 12 core biopsies, respectively. The positive DRE rate in both groups was around 25 %. The authors conclusion is, 6 core prostate biopsy techniques should be considered outdated, and, about 50% of patients with increased PSA have prostate cancer. These two sentences deserve no further emphasis. Dr. Andreas Böhle Professor of Urology HELIOS Agnes Karll HospitalBad Schwartau, Germany FEMALE UROLOGY _____________________________________________________________The tensile properties of tension-free vaginal tape and cadaveric fascia lata in an in vivo rat model Spiess PE, Rabah D, Herrera C, Singh G, Moore R, Corcos J Department of Urology, McGill University, Montreal, Canada BJU Int. 2004;93: 171-3 Objective: To examine the tensile properties (break load and maximum average load), after in vivo implantation in a rat animal model, of tension-free vaginal tape (TVT) and cadaveric fascia lata (CFL), as pubovaginal slings of these materials have become popular for treating stress urinary incontinence.Materials and Methods: Twenty Sprague-Dawley rats (300-400 g) had 1 x 2 cm strips of commercially available TVT and CFL implanted on the right and left anterior abdominal wall, respectively. Half of the animals were then killed at 6 weeks and the remainder at 12 weeks, after which the strips of TVT and CFL were removed and their tensile properties measured using a tensiometer. The tensile strength of TVT and CFL strips maintained only in normal saline served as controls.Results: The TVT strips had a mean break load of 0.740 kg in the control and only 0.390 kg for CFL (P < 0.05). At 6 weeks the TVT material had a mean (sd) maximum average load of 0.634 (0.096) kg and a mean break load of 0.589 (0.249) kg, whereas the respective values for the CFL were 0.323 (0.198) and 0.167 (0.063) kg (P < 0.05). Similarly at 12 weeks, TVT had a greater mean maximum average and break load than CFL, at 0.742 (0.052) and 0.274 (0.126), and 0.737 (0.056) and 0.185 (0.128) kg, respectively.Conclusion: This is the first study to assess the tensile properti...