Reconstructive urology

Abstract

The authors found that relaxation mechanisms of urethral striated and smooth muscle during reflex bladder contractions are impaired in diabetes mellitus. They proposed that this defect coupled with bladder hypoactivity could result in inefficient voiding and bladder overdistention in diabetes mellitus. The authors also proposed that therapy with L-arginine might be useful for partially restoring the urethral relaxation mechanism in diabetes mellitus.