“…Varicocele is defined as a pampiniform plexus vein dilation with retrograde blood flow in the spermatic vein. It is considered the main treatable cause of male infertility ( 1 , 2 ) and its pathophysiology involves several mechanisms that can disturb the male fertility potential. Therefore, studies have demonstrated that venous dilatation increases the scrotal temperature, and leads to the occurrence of venous reflux, venous stasis, hypoxia, and oxidative stress ( 3 ).…”