Editorial Comment: Intradetrusor botulinum toxin injections (300 units) for the treatment of poorly compliant bladders in patients with adult neurogenic lower urinary tract dysfunction
Abstract:Intradetrusor onabotulinum toxin A (BTX) is the most effective minimally invasive treatment to reduce neurogenic detrusor overactivity (DO) (1) and has been proven effective in patients with neurourological disorders in phase III randomized placebo-controlled trials (2, 3). On-label dosage for neurogenic DO is 200 Units. Patients with spinal dysraphism and spinal cord injury (SCI) have a higher risk of developing upper urinary tract deterioration (UUTD). Urodynamic findings such as reduced compliance and high … Show more
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