Synthetic slings in the treatment of urinary incontinence: lessons learned and future perspectives

Riccetto, Cássio

doi:10.1590/s1677-5538.ibju.2020.04.04

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…21 Nonetheless, mesh-related adverse events are associated with the midurethral sling. 22,23 In response to surgical complications involving the use of transvaginal mesh for pelvic organ prolapse, the United States Food and Drug Administration (US FDA) issued a safety communication in 2011 24 and, since April 16, 2019, has banned the production and sale of transvaginal mesh for pelvic organ prolapse. 25 By early 2015, over 70,000 women in the US had filed lawsuits alleging complications associated with transvaginal mesh used for both SUI and pelvic organ prolapse surgical procedures.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for 5-Year Complications after Midurethral Sling Surgery for Stress Urinary Incontinence: A Retrospective Cohort Study from Taiwan

Chou

HSIA

HWANG

et al. 2022

Preprint

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Background: Midurethral sling surgery is the current gold standard worldwide for stress urinary incontinence (SUI) surgery. However, concerns surround mesh-related adverse events associated with the midurethral sling. The decision to use the midurethral sling for surgical treatment has become a challenging one for clinicians, surgeons and patients. Objectives: We sought to determine the factors for 5-year complications after midurethral sling surgery, to improve the clinical decision-making process. Study Design: Records were reviewed from a total of 1,961 female patients who underwent their first midurethral sling surgery for SUI between 2003 and 2018 at a single teaching hospital in Taiwan. A multivariable Cox proportional hazard model calculated the hazard ratios of risk factors for surgical complications, after adjusting for confounders. Results: Surgical complications (i.e., secondary surgery and urinary retention) occurred in 93 (4.7%) patients within 5 years following the index operations. These patients were more likely to be older, to have a history of menopausal syndrome within 1 year prior to the index operation,hormone replacement therapy (HRT), slower average flow rate, and longer voiding time compared with patients without surgical complications. In the multivariate analysis, menopausal syndrome or HRT (adjusted hazard ratio, 1.794; 95% confidence interval, 1.055–3.050, p=0.0390) was significantly associated with surgical complications at 5 years, after adjusting for age, gender, diabetes, average flow rate, and sling type. Conclusion: Our findings suggest that a history of menopausal syndrome within 1 year prior to surgery or a medication history of HRT may be risk factors associated with surgical complications

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Section: Introductionmentioning

confidence: 99%

Risk Factors for 5-Year Complications after Midurethral Sling Surgery for Stress Urinary Incontinence: A Retrospective Cohort Study from Taiwan

Chou

HSIA

HWANG

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

Risk factors for 5-year complications after midurethral sling surgery for stress urinary incontinence: a retrospective cohort study from Taiwan

Chou,

Hsia,

Hwang

et al. 2023

Sci Rep

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Midurethral sling surgery is the current gold standard worldwide for stress urinary incontinence (SUI) surgery, with over 90% of surgeons worldwide using the midurethral sling for SUI between 2008 and 2018. However, concerns surround mesh-related adverse events associated with the midurethral sling. The decision to use the midurethral sling for surgical treatment has become a challenging one for clinicians, surgeons and patients. We sought to determine the factors for 5-year complications after midurethral sling surgery, to improve the clinical decision-making process. Records were reviewed from a total of 1961 female patients who underwent their first midurethral sling surgery for SUI between 2003 and 2018 at a single teaching hospital in Taiwan. A multivariable Cox proportional hazard model calculated the hazard ratios of risk factors for surgical complications, after adjusting for confounders. Surgical complications (i.e., secondary surgery and urinary retention) occurred in 93 (4.7%) patients within 5 years following the index operations. These patients were more likely to be older, to have a history of menopausal syndrome within 1 year prior to the index operation, a medication history of oral antidiabetic drug use, hormone replacement therapy (HRT), slower average flow rate, and longer voiding time compared with patients without surgical complications. In the multivariate analysis, HRT (adjusted hazard ratio, 1.787; 95% confidence interval, 1.011–3.158, p = 0.04) was significantly associated with surgical complications at 5 years, after adjusting for age, gender, diabetes, menopause syndrome, average flow rate, and sling type. Our findings suggest that a medication history of HRT may be a risk factor associated with surgical complications, especially urinary retention, at 5 years in women undergoing midurethral sling surgery for SUI.

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Synthetic slings in the treatment of urinary incontinence: lessons learned and future perspectives

Cited by 2 publications

References 22 publications

Risk Factors for 5-Year Complications after Midurethral Sling Surgery for Stress Urinary Incontinence: A Retrospective Cohort Study from Taiwan

Risk Factors for 5-Year Complications after Midurethral Sling Surgery for Stress Urinary Incontinence: A Retrospective Cohort Study from Taiwan

Risk factors for 5-year complications after midurethral sling surgery for stress urinary incontinence: a retrospective cohort study from Taiwan

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