“…Uncommon sites include the small and large bowel, brain and spinal cord, kidneys, and spleen 4 . Superior performance of PSMA-targeted PET imaging has resulted in several reports of unusual biopsy-proven metastases, including mediastinal lymph nodes, ductus deferens, testicle, abdominal wall, and pleura 5,6 . We present a case of biopsy-proven prostate cancer metastasis to the rectal submucosa that was initially identified by PSMA-targeted PET imaging, which has been rarely reported 5 .…”