“…4 To date, only 23 of these cases have been reported, including ours (Table 1 ). 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 Of these cases, half had a history of long‐standing ADT for conventional‐type prostate AC, suggesting acquired neuroendocrine differentiation. The rest is considered as de novo LCNEC, which can be classified into two types: pure and combined with AC.…”