Tumor-like appearance of Spermatic Granuloma

Garrido-Abad, Pablo; Díaz-Menéndez, A.; García-Martín, Luis; Senra-Bravo, Isabel; Fernández-Arjona, Manuel

doi:10.1590/s1677-5538.ibju.2018.0676

Cited by 3 publications

(6 citation statements)

References 7 publications

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“…Spermatic granuloma is a granulomatous disease caused by inflammatory and histiocytic reactions resulting from sperm spilling into the interstitial tissue. [1,2] Sperms are antigens that spill into the body, causing the body to produce antibodies. [4] Spermatic granulomas mainly comprise lymphocytes, histocytes, and sperm.…”

Section: Discussionmentioning

confidence: 99%

“…Spermatic granuloma is a nonbacterial inflammation resulting from damaged sperm in the vas deferens wall that spills into the matrix outside of the vas deferens. It usually occurs in the epididymis, testes, and vas deferens; moreover, the epididymis is the most common site [1,2] . There are no specific clinical manifestations or biochemical examinations for the diagnosis of spermatic granuloma; thus, the diagnosis of spermatic granuloma mainly depends on pathological examination rather than clinical diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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MRI features of testicular spermatic granuloma

Liu

Yang²,

Huo³

et al. 2022

Medicine

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This is a meta-analysis to compare the results between laminoplasty and laminectomy followed by fusion for the patients with multilevel cervical compressive myelopathy. An extensive search of literature was performed in MEDLINE, Embase, the Cochrane library, CNKI, and WANFANG. The following outcome measures were extracted: the Japanese Orthopaedic Association (JOA) scores, cervical curvature index (CCI), visual analog scale (VAS), cervical lordosis (C2–7), complications, blood loss, and operation time. Data analysis was conducted with RevMan 5.3 and STATA 12.0. A total of 23 studies comprising 774 and 743 patients treated with laminoplasty and laminectomy followed by fusion, respectively, were included in the final analysis. The pooled analysis showed that there was no significant difference in preoperative JOA scores [P = 0.89], postoperative JOA scores [P = 0.13], JOA scores improvement rate [P = 0.27], preoperative CCI [P = 0.15], postoperative CCI [P = 0.14], preoperative VAS [P = 0.41], postoperative VAS [P = 0.52], preoperative cervical lordosis (C2–7) [P = 0.46], postoperative cervical lordosis (C2–7) [P = 0.67], total complications [P = 0.07], axial pain [P = 0.94], and blood loss [P = 0.51]. However, there were significant difference in operation time (WMD = −19.57 [−32.11, −7.02], P = 0.002) and C5 palsy (OR = 0.26 [0.15, 0.44], P < 0.001). As compared with laminectomy followed by fusion, expansive laminoplasty showed no significant differences in JOA scores, CCI, ROM, VAS, cervical lordosis (C2–7), axial pain, total complications, and blood loss, but shorter operation time and fewer C5 palsy.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

MRI features of testicular spermatic granuloma

Liu

Yang²,

Huo³

et al. 2022

Medicine

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“…35,39 They typically present as a palpable mass or are detected during surgical reversal of vasectomies, but some may present with pain. 40,41 They can occur anywhere along ductal system, but are most frequently seen at the ends of the divided vas deferens post vasectomy and less often at the vasoepididymal loop. They are typically 1 cm or smaller, but range in size from microscopic to 4 cm.…”

Section: Inflammationmentioning

confidence: 99%

“…They are typically 1 cm or smaller, but range in size from microscopic to 4 cm. 42 The sonographic appearance has not been studied systematically, but case series and anecdotal experience indicate that they often appear as a solid, well-defined, hypoechoic, heterogeneous mass 40,[42][43][44][45] (Fig. 22A and video 22B, http://links.lww.com/RUQ/A253).…”

Section: Inflammationmentioning

confidence: 99%

Ultrasound of the Normal and Abnormal Vas Deferens

Kerr

Middleton²

2022

Ultrasound Quarterly

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The extrapelvic portion of the vas deferens is readily visible with ultrasound but often overlooked. Several publications have described the scanning technique and the normal anatomy of the vas deferens. Sonographic evaluation of the vas deferens provides critical information in the workup of male infertility. Obstruction, inflammatory conditions, and neoplasms of the vas deferens can also be diagnosed with ultrasound. Knowledge of the normal and abnormal appearance of the vas deferens improves scans of the scrotum and expands the conditions that can be recognized and accurately diagnosed with ultrasound.

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“…The first case was reported in 1949[ 1 ] and ultrasonographic findings were first described in 1982[ 2 ]. In the past 10 years, only a few cases of SGs have been reported[ 3 - 5 ], let alone the cases of bilateral and postoperative recurrent SGs. According to the existing literature, SG is common in the epididymis and occasionally occurs in the spermatic cord and testes.…”

Section: Introductionmentioning

confidence: 99%

Bilateral occurrence of sperm granulomas in the left spermatic cord and on the right epididymis: A case report

Lv¹,

Xie²,

Fan³

et al. 2022

World J Clin Cases

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BACKGROUND Sperm granuloma is a rare disease in clinical andrology and its incidence is still unclear worldwide. According to the existing literature, sperm granuloma often occurs unilaterally. Clinical and ultrasound features are similar to epididymal tuberculosis, chronic epididymitis and other diseases. Sperm granuloma is usually diagnosed based on postoperative histopathological and immunohistochemical examination. CASE SUMMARY A 46-year-old man was admitted to the hospital due to the presence of a left scrotal mass for 3 mo and aggravation of pain for 1 wk. The lesions at both sites were surgically resected. Postoperative pathological examination showed that the left spermatic cord mass and the right epididymal mass were consistent with sperm granuloma. The sperm granulomas then recurred 3 mo after surgery. There is little change in the local mass so far. CONCLUSION The case report is helpful for our understanding of this disease. In clinical diagnosis, it should be distinguished from epididymal tuberculosis, chronic epididymitis and other diseases. Color Doppler ultrasound can be used as a preferred examination method but postoperative pathological examination is still needed for diagnosis.

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Tumor-like appearance of Spermatic Granuloma

Cited by 3 publications

References 7 publications

MRI features of testicular spermatic granuloma

MRI features of testicular spermatic granuloma

Ultrasound of the Normal and Abnormal Vas Deferens

Bilateral occurrence of sperm granulomas in the left spermatic cord and on the right epididymis: A case report

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