Focal therapy will be the next step on prostate cancer management? | Opinion: No

Matheus, Wagner Eduardo; Ferreira, Ubirajara

doi:10.1590/s1677-5538.ibju.2017.06.03

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…In their review of the literature, Ganzer et al concluded that posterior prostate lesions were most amenable to focal therapy using HIFU; cryotherapy was better for anterior tumors; and apical lesions were best treated with focal brachytherapy. The major competitor to the use of HIFU is active surveillance: in other words, watching and waiting rather than treating . Barayan et al found that active surveillance of unfavorable disease features in patients with localized low‐ to intermediate‐risk prostate carcinoma would prevent unnecessary treatment, including HIFU hemiablation.…”

Section: Comparison With Other Focal Therapiesmentioning

confidence: 99%

Histotripsy: The Next Generation of High‐Intensity Focused Ultrasound for Focal Prostate Cancer Therapy

Dubinsky

Khokhlova

et al. 2019

J of Ultrasound Medicine

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This article reviews the most current methods and technological aspects of highintensity focused ultrasound (HIFU), which is termed histotripsy. The rationale for focal therapy for prostate carcinoma rather than prostatectomy, which is being used extensively throughout Europe and Asia, is presented, and an argument for why HIFU is the modality of choice for primary therapy and recurrent disease is offered. The article presents a review of the technical advances including higher ultrasound beam energy than current thermal HIFU which allows for more accurate tissue targeting, less collateral tissue damage, and faster treatment times. Finally, the article presents a discussion about the advantage of ultrasound guidance for histotripsy in preference to magnetic resonance imaging guidance primarily based on cost, ease of application, and portability.

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Section: Comparison With Other Focal Therapiesmentioning

confidence: 99%