Recto-urethral fistula presenting as fever of unknown origin: a rare complication of prostatic abscess

Lee, Sun Hwa; Yun, Seong Jong; Ryu, Seokyong

doi:10.1590/s1677-5538.ibju.2017.0468

Cited by 1 publication

(1 citation statement)

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“…Given that FUO may be caused by infectious, inflammatory, malignant, and miscellaneous disorders, clinicians often order non-clue-based imaging and specific testing early at the onset of FUO, and this approach may be inefficient or misleading [28]. In recent years, serious complications and even deaths from many diseases associated with FUO have been reported [29][30][31]. FUO is a persistent clinical problem that often confuses clinicians to the point that physicians need to deal with different diseases characterized by FUO at a great cost.…”

Section: Discussionmentioning

confidence: 99%

Human brucellosis and fever of unknown origin

Song

Wang

et al. 2022

BMC Infect Dis

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Background Human brucellosis has become one of the major public health problems in China, and increases atypical manifestations, such as fever of unknown origin (FUO), and misdiagnosis rates has complicated the diagnosis of brucellosis. To date, no relevant study on the relationship between brucellosis and FUO has been conducted. Methods We retrospectively reviewed the medical charts of 35 patients with confirmed human brucellosis and prospectively recorded their outcomes by telephone interview. The patients were admitted to the Second Affiliated Hospital of Nanchang University between January 01, 2013 and October 31, 2019. Patient data were collected from hospital medical records. Results The percentage of males was significantly higher than that of female in FUO (78.95% vs. 21.05%, P < 0.05), and 80% of the patients had a clear history of exposure to cattle and sheep. Moreover, 19 (54%) cases were hospitalized with FUO, among which the patients with epidemiological histories were significantly more than those without (P < 0.05). The incidence of toxic hepatitis in FUO patients was higher than that in non-FUO patients (89% vs. 50%, P < 0.05). Meanwhile, the misdiagnosis rate was considerably higher in the FUO group than in the non-FUO group (100% vs. 63%; P < 0.05). Conclusion Brucellosis is predominantly FUO admission in a non-endemic area of China, accompanied by irregular fever and toxic hepatitis. Careful examination of the epidemiological history and timely improvement of blood and bone marrow cultures can facilitate early diagnosis and prevent misdiagnosis.

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