Inflammatory pseudotumor of kidney: a challenging diagnostic entity

Child inflammatory myofibroblastic tumor of the kidney misdiagnosed as Wilms' tumor: case report

“…In the urogenital tract, IMT mainly affects the urinary bladder, but rarely the kidney. The clinical manifestations were not typical, mainly manifested as lumbago, gross hematuria, and fever [7 , 8] . In our case, the patient presented with abdominal pain accompanied with a fever.…”

“…The current WHO classification of this lesion is intermediate grade malignant, with the potential of recurrence and rare metastasis. Many studies tried to link the aggressive behavior with certain molecular markers such as P-53 and translocations of ALK-1 gene, yet inconsistent results among these studies make a prediction of prognosis difficult [7] . The fever may indicate a chronic inflammatory process in our case.…”

Child inflammatory myofibroblastic tumor of the kidney misdiagnosed as Wilms’ tumor : Case report

“…6 Immunohistochemical analyses confirmed that vimentin, muscle-specific actin, smooth muscle actin and CK were positive in IMT. 7 Etiology has been linked to surgery, vascular causes, chronic inflammation, infection, trauma, immune disorders and autoimmune reaction, however, it remains unclear. 8 The occasionally seen aggressive features and distant metastasis cannot be well explained by the inflammatory etiology alone.…”

A Case of Renal Inflammatory Pseudotumor Leading to Nephrectomy

“…Macroscopic samples manifested a wellcircumscribed, nonencapsulated, homogenous mass with yellow cut surfaces. 3,12 Histological evaluation found both acute and chronic inflammation cells in the IPT lesion, including lymphocytes, plasma cells, myofibroblastic spindle cells, and variable amounts of fibrosis. 1,7 Some IPTs are associated with immunoglobulin (Ig) G4-related disease.…”

“…Renal IPT is quite rare. 1 - 3 Other names for IPT include inflammatory myofibroblastic tumor, xanthomatous pseudotumor, plasma cell granuloma, inflammatory myofibroblastic proliferation, and myofibroblastoma. 4 Most patients with IPT have nonspecific symptoms, such as flank pain, hematuria, and fever.…”