A large 15 - year database analysis on the influence of age, gender, race, obesity and income on hospitalization rates due to stone disease

Mello, Marcos Figueiredo; Marchini, Giovanni Scala; Camara, Cesar; Danilovic, Alexandre; Levy, Renata Bertazzi; Eluf-Neto, José; Srougi, Miguel; Mazzucchi, Eduardo

doi:10.1590/s1677-5538.ibju.2015.0743

Cited by 5 publications

(64 citation statements)

References 15 publications

(20 reference statements)

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“…[3] The mean age in our study of 48.2 years ± 12.4 (SD) was similar to that reported by Aghamir et al [6] with majority of their patients in the middle-age group. There is a slight female preponderance in our study; this is similar to the finding by Mello et al [7] but at variance with most of the other previous studies which reported male preponderance. [38] Estrogen has been shown to be protective for stone;[9] the female preponderance in our study can be explained by the fact that majority of the patient were middle-age group during which many of the female were peri/postmenopausal.…”

Section: Discussionsupporting

confidence: 92%

Endoscopic management of ureteric stones: Our initial experience

Alabi¹,

Jeje²,

Ogunjimi³

et al. 2019

Niger J Surg

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Aims: The aim of this study is to present our initial experience with intracorporeal pneumatic ureterolithotripsy highlighting the pattern of patients’ clinical presentation, techniques, and limitation of the procedure. Materials and Methods: This is a retrospective study of cases of ureteric stones managed over a period of 18 months in a private hospital. Data obtained include patients’ sociodemography, clinical presentation, stone burden, procedural technique, complication, and need for a secondary procedure. Data were analyzed using the Statistical Package for the Social Sciences version 21. Results: The total number of patients managed was 20 with an age range of 28–75 years and a mean of 48.2 ± 12.4 years. Majority of them, i.e., 11 (55%) were middle aged. Female gender was more predominant, 11 (55%). Flank pain was the most common mode of presentation. Right-sided stone occurred in 9 (45%), left sided in 7 (35%), and bilateral in 4 (20%). Stone location was in the upper ureter in 4 (16.7%), mid-ureter in 7 (29.2%), and lower ureter in 13 (54.2%). The stone size ranged from 6 to 18 mm with a mean of 9.7 ± 2.5 mm. Four patients (20%) required initial bilateral ureteric stenting before definitive procedure to allow for recovery from sepsis and/or nephropathy. All patients had double-J stenting and were discharged 2 days after the procedure. The procedure was successful in 19 (95%) with 100% stone clearance rate and complete resolution of symptom without any complication. One patient (5%) had a very hard upper ureteric stone which retropulsed into the renal pelvis requiring open nephrolithotomy. Conclusion: Endoscopic treatment of ureteric stone with intracorporeal pneumatic lithotripsy is a safe and effective treatment modality. It is, however, limited in the management of hard upper ureteric stone, especially those that are close to the pelviureteric junction due to the risk of retropulsion of the stone into the kidney.

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Section: Discussionsupporting

confidence: 92%

Endoscopic management of ureteric stones: Our initial experience

Alabi¹,

Jeje²,

Ogunjimi³

et al. 2019

Niger J Surg

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“…From 2017 to 2019, a mean increment of 6.4% hospital admissions was observed, reaching 90.170 events. These data reinforce previous surveys demonstrating a progressive increase in urolithiasis admissions over the years in Brazil (12). Conversely, during the COVID-19 outbreak, there was a significant decrease in hospital admissions with urolithiasis diagnosis compared to preceding years (p <0.0001, Figure -1).…”

Section: Resultssupporting

confidence: 89%

COVID-19: The impact on urolithiasis treatment in Brazil

et al. 2022

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Introduction: It has been more than a year since the fi rst case of Covid-19 was diagnosed in Brazil, and its most problematic feature is the oversaturation of the healthcare system capacity. Urolithiasis is a disease that requires timely and appropriate management. The present study aimed to evaluate the impact of the pandemic in hospital admissions for urolithiasis in the Brazilian public healthcare system. Materials and Methods: In this cross-sectional study, hospital admissions were obtained from the Brazilian Public Health Information system. All hospital admissions associated with urolithiasis diagnosis (ICD-10 N20) between March 2017 and February 2021 were analyzed.Results: During the COVID-19 outbreak, there was a signifi cant decrease in hospital admissions (p<0.0001). More than 20.000 patients probably did not have the opportunity to undergo their surgeries. The impact of the COVID-19 outbreak on women's admissions was signifi cantly more intense than for men, reducing from 48.91% to 48.36% of the total (p=0.0281). The extremes of age seemed to be more affected, with patients younger than 20 years and older than 60 years having a signifi cant reduction in access to hospital services (p=0.033). Conclusions: In conclusion, we have noticed a considerable reduction in overall admissions for the treatment of urolithiasis in the Brazilian public healthcare system during the fi rst year of the Covid-19 pandemic. Women and individuals older than 60 years were especially affected. In contrast, we noted a rise in urgent procedures, comparing with the average of the corresponding period of the three previous years. Recovery plans will be needed while returning to activities to handle the impounded surgical volume.

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“…Consistent with the literature, our findings support that the incidence of urolithiasis was greater in the younger individuals even though there was no statistical significance. The increased incidence of urolithiasis in middle age may be associated with the development of metabolic syndrome, increased dietary calcium, sucrose or protein intake, and increased working time [ 2 , 47 ].…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence means any stone during a period of life and the lifetime prevalence of urolithiasis would increase with incremental age [ 1 ]. The incidence of urolithiasis varies with age and it is rare before age 20; nevertheless, urolithiasis would peak between age 40–60 and then decrease after age 65 [ 2 ]. The annual incidence of urolithiasis is reported to range between 0.5% and 1.5% in Western countries, but the epidemiological studies of incidence in Taiwan is limited [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Association between chronic pancreatitis and urolithiasis: A population-based cohort study

2018

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PurposeChronic pancreatitis (CP) can cause fat or bile acid malabsorption due to exocrine insufficiency. Fat or bile acid malabsorption has been reported to increase the risk of urolithiasis through increased intestinal oxalate absorption. However, no studies have reported an association between CP and urolithiasis.MethodsWe identified 15,848 patients (age: ≥20 years) diagnosed as having CP between 2000 and 2010 from the National Health Insurance Research Database as the study cohort. Beneficiaries without a history of CP were randomly selected and propensity-matched with the study cohort in a 1:4 ratio according to age; sex; comorbidities of hyperlipidemia, diabetes, obesity, hypertension, chronic obstructive pulmonary disease, alcohol-related illness, stroke, and coronary artery disease; and the index date. The prevalence of inflammatory bowel disease (0.44%), hyperparathyroidism (0.10%), or end stage renal disease (1.55%) in CP patients was low, but these comorbidities were also considered in the analysis. All patients were followed until the end of 2011 or withdrawal from the National Health Insurance program to determine the incidence of urolithiasis.ResultsThe cumulative incidence of urolithiasis was higher in the CP cohort than that in the non-CP cohort (log-rank test, P < 0.001) with a 1.89-fold risk of urolithiasis (95% confidence interval [CI] = 1.74–2.06). The prevalence of CP was higher in men (81.9%) and in patients younger than 49 years (63.5%; mean age: 48.5 ± 15.3 years). CP was associated with the development of urolithiasis in each age group (≤49 years: aHR = 2.00, 95% CI = 1.81–2.22; 50–64 years: aHR = 1.71, 95% CI = 1.40–2.09; ≥65 years: aHR = 1.54, 95% CI = 1.20–1.98) and each sex (women: aHR = 2.10, 95% CI = 1.67–2.66; men; aHR = 1.86, 95% CI = 1.70–2.04). Among the patients without comorbidities, the rate of urolithiasis increased from 2.93/1,000 person-years in non-CP patients to 8.28/1,000 person-years in CP patients. Among the patients with comorbidities, the rate of urolithiasis increased from 6.12/1,000 person-years in non-CP patients to 10.9/1,000 person-years in CP patients. The contribution of CP to the relative risk of urolithiasis was greater in patients without comorbidities (without comorbidities: aHR = 2.81, 95% CI = 2.30–3.44) than in those with comorbidities (aHR = 1.76, 95% CI = 1.61–1.94).ConclusionCP is associated with urolithiasis in this population-based cohort study. The contribution of CP to the relative risk of urolithiasis was even greater in patients with a lower risk of urolithiasis, such as those without other comorbidities. Our findings warrant a survey and education on urolithiasis for patients with CP.

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A large 15 - year database analysis on the influence of age, gender, race, obesity and income on hospitalization rates due to stone disease

Cited by 5 publications

References 15 publications

Endoscopic management of ureteric stones: Our initial experience

Endoscopic management of ureteric stones: Our initial experience

COVID-19: The impact on urolithiasis treatment in Brazil

Association between chronic pancreatitis and urolithiasis: A population-based cohort study

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