Vasectomy Reversal Must be the First Step for a Man Who had a Vasectomy and Wants a Children from a New Marriage? Opinion: No

Chiles, Kelly A.

doi:10.1590/s1677-5538.ibju.2015.06.04

Cited by 4 publications

(4 citation statements)

References 11 publications

(12 reference statements)

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“…Reproductive specialists commonly encounter a clinical scenario of couples with advanced maternal age and a male partner with a history of vasectomy. Just as in other women's fertility scenarios, the chances for pregnancy with IVF decrease precipitously in women after the age of 35 (12)(13)(14). Such patients may experience considerable anxiety and distress because of these factors, and it is important for the clinician to be familiar with available data so as to best counsel them.…”

Section: Advanced Maternal Age (>35 Years)mentioning

confidence: 99%

Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis

Dubin

White

Ory

et al. 2021

Fertility and Sterility

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Section: Advanced Maternal Age (>35 Years)mentioning

confidence: 99%

Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis

Dubin

White

Ory

et al. 2021

Fertility and Sterility

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“…Si l'on considère qu'un succès correspond à la présence de spermatozoïdes dans l'éjaculat, il est estimé entre 44 et 97%. Toutefois, le taux de grossesse spontanée suite à cette reperméabilisation se situe entre 26 et 70% (en fonction des études) (11,55). -On peut proposer au patient des techniques d'AMP après ponction intra-testiculaire ou intra-épididymaire de spermatozoïdes (11).…”

Section: Des Regretsunclassified

“…Cette technique est beaucoup plus onéreuse que la reperméabilisation chirurgicale. Elle est cependant plus demandée par les couples (48,55).…”

Section: Des Regretsunclassified

La vasectomie, une contraception occultée

Rostam

2017

Vocation Sage-femme

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“…Progressive inflammatory scarring of the mucosa is considered a contributing factor to late failure, indicating the need for exploration into anti-inflammatory interventions ( 3 , 6 ). Although a study by Machen et al demonstrated the efficacy of a high-dose prednisone regimen, concerns arise regarding the associated immunosuppressive effects ( 8 ).…”

Section: Introductionmentioning

confidence: 99%

Low-dose prednisone is an effective rescue for deteriorating semen parameters following vasovasostomy

White,

Campbell,

Deebel

et al. 2024

Int. braz j urol.

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Objective: This retrospective study aimed to evaluate the effectiveness of low-dose prednisone as a rescue therapy for patients with deteriorating semen parameters following vasovasostomy. Materials and Methods: Electronic medical records were queried at the University of Miami with documented CPT code 55400 (Bilateral Vasovasostomy) between January 2016 and April 2023. Records were then reviewed to identify patients who demonstrated ≥50% decrease in semen parameters, specifically sperm concentration, motility and total motile sperm count. Patients who were treated with 6 weeks of low-dose prednisone were identified, and baseline semen parameters and subsequent changes after prednisone therapy were assessed. A Mann-Whitney U Test was used to compare semen parameter changes before and after prednisone. Adverse effects associated with prednisone were monitored. Results: A total of 8 patients were identified with deteriorating semen parameters who were treated with 6 weeks of low-dose prednisone. Following prednisone therapy, all patients demonstrated improvements in total motile sperm count (TMSC), with a median improvement of 6 million. The median relative improvement in TMSC was 433%. Sperm concentration and motility also improved compared to post-operative baseline. No adverse effects were reported during the treatment period. Conclusions: Low-dose prednisone therapy appears to be a safe and effective intervention for managing deteriorating semen parameters following VV. The observed improvements in TMSC suggest the potential of prednisone to rescue patients with delayed failure after VV. Further research with larger sample sizes is warranted to confirm the safety and efficacy of low-dose prednisone as a rescue therapy in this specific patient population. Optimizing VV outcomes is crucial in male infertility, and further exploration of steroid therapy and innovative biotechnologies is warranted.

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Vasectomy Reversal Must be the First Step for a Man Who had a Vasectomy and Wants a Children from a New Marriage? Opinion: No

Cited by 4 publications

References 11 publications

Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis

Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis

La vasectomie, une contraception occultée

Low-dose prednisone is an effective rescue for deteriorating semen parameters following vasovasostomy

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