Acute and chronic mesenteric ischemia: MDCT findings

Serpa, Bruna S.; Tachibana, Adriano; Baroni, Ronaldo Hueb; Aun, Ricardo; Funari, M.B.G.

doi:10.1590/s1677-54492010000300011

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…In Emara's study [20], the most prevalent MS intestinal findings in 30 patients with positive CT angiographic findings were bowel wall thickening in 16 patients (53.3%). These findings more or less matched with those reported by Serpa et.al in 2010 [22] followed by diminished wall enhancement was described in the contrast enhanced CT (CECT) series of 15 patients representing (50%) of cases, which is matched with Wong. [23].…”

Section: Discussionsupporting

confidence: 90%

Multidetector Computed Tomography in Diagnosis of Mesenteric Vascular ‎Occlusion

Dalal

Dawoud

Elnemr

et al. 2021

JAMMR

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Background: Multidetector computed tomography (MDCT) has high sensitivity and ‎specificity for diagnosing acute primary mesenteric ischemia (MI). MDCT findings vary ‎widely depending on the cause and underlying pathophysiology. MDCT findings of ‎mesenteric ischemia should be characterized on the basis of the cause‏ ‏that lead to early ‎diagnosis and intervention. Aim: The aim of the study was to assess the impact of different MDCT phases in ‎diagnosis of mesenteric vascular occlusion (MVO).‎ Patients and Methods: This study that was carried out on 20 patients with suspected mesenteric vascular ‎occlusion who were referred to Tanta University Hospitals and General Surgery ‎Department during a period one year starting from May 2018 till May 2019.‎ Results: Out of the 20 studied patients, 11 (55%) of them was male and 9 (45‎‎%) was female, the age of the studied patients ranged from 40 to 73 years old ‎with mean age 57.10 ± 8.85 years. In our study the predisposing factors for MVO were as follow 6 (30%) had ‎Primary thrombosis, 9 (45%) had cirrhosis, 8 (40%) had Portal hypertension, ‎‎4 (20%) had DM, 4 (20%) had Atherosclerosis, and 2 (10%) had ischemic heart ‎disease.‎ Conclusion: Acute and chronic mesenteric ischemia are morbid conditions that are challenging to ‎diagnose. Patients present with variable, nonspecific signs and symptoms, and the ‎physical examination is often benign. A high index of clinical and radiologic suspicion ‎is thus required for diagnosis MDCT is an accurate, fast, and non-invasive ‎technique which should be used in clinically suspected patients with MVO in order to ‎confirm the diagnosis identify the aetiology and in addition assessing the bowel loop ‎status for adequate management with good prognosis.‎ Familiarity with the MDCT imaging manifestations of mesenteric ischemia allows ‎for a more precise, prompt diagnosis, early institution of therapy and potentially ‎improved patient outcomes.‎

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Section: Discussionsupporting

confidence: 90%

Multidetector Computed Tomography in Diagnosis of Mesenteric Vascular ‎Occlusion

Dalal

Dawoud

Elnemr

et al. 2021

JAMMR

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“…At those areas the integrity of cell membrane could suffer with hypoxia and the cell itself could miss the ideal amount of energy production as well as accumulate, direct or indirectly, metabolites and inflammatory mediators causing cellular dysfunction [9][10][11][12][13][14][15] .…”

Section: Introductionmentioning

confidence: 99%

Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1

Brasileiro

Inoye²,

Aydos³

et al. 2013

Acta Cir. Bras.

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PURPOSE:To investigate the small intestinal tissue alterations in rats submitted to ischemia and tissue reperfusion using pentoxyfilline or prostaglandin E1. METHODS:Thirty five Wistar rats were used, distributed into group control (A) n=10 were submitted to intestinal ischemia and reperfusion during 60 minutes and no one drug have been utilized. In the group pentoxyfilline (B) n=10 have been utilized during tissue ischemia and reperfusion as well as prostaglandin E1 (C) n=10, but separately . In the group sham (D) n=5, the animals were submitted to surgical. After euthanasia of the animals, a segment of the small intestine was cut, stained by hematoxilin-eosin and histological analysis according to Chiu criteria. RESULTS:Histological results showed that using pentoxyflline or prostaglandin E1 the results during tissue reperfusion were better, since the levels of criteria from Chiu that predominated were level 2 and 3, indicating less tissue damage in comparison to the control group (group A) that showed levels 4 and 5, what means more severe histological tissue alterations. CONCLUSION:Use of pentoxyfilline or prostaglandin E1 promoted a beneficial effect during intestinal reperfusion, demonstrated by less severe histological lesions in the small intestine mucosa of rats submitted to ischemia and tissue reperfusion when helped by the drugs.

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