Pre-surgical mood disorders associated to worse post-surgical seizure outcome in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis

Filho, Gerardo Maria de Araújo; Gomes, Francinaldo Lobato; Mazetto, Lenon; Marinho, Murilo Martinez; Tavares, Igor Melo; Caboclo, Luís Otávio Sales Ferreira; Yacubian, Elza Márcia Targas; Centeno, Ricardo Silva

doi:10.1590/s1676-26492012000100006

Cited by 4 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a large cohort of subjects with newly diagnosed epilepsy, a history of psychiatric comorbidity was associated with progression to refractory disease [42]. De Araújo Filhoa et al [65] found a statistically significant association between the absence of pre-surgical psychiatric disorder and a favorable seizure outcome which was reported by other researchers [18,46,66]. Thus it is essential to have a pre and post surgical psychiatric assessment of patients.…”

Section: Presurgical and Postsurgical Psychiatric Assessmentmentioning

confidence: 82%

Is psychiatric assessment essential for better epilepsy surgery outcomes?

Sawant

Ravat

Muzumdar

et al. 2016

International Journal of Surgery

View full text Add to dashboard Cite

Epilepsy surgery is one of the most accepted and beneficial treatment for resistant epilepsies. However there is some variability in the comprehensive epilepsy care programs offered globally. Many centers do not do a psychiatric assessment unless required. It is now evident from a large body of research that epilepsy is associated with psychiatric morbidity which is also seen in patients considered for epilepsy surgery. There is also evidence to state that the risk for worsening or de novo psychiatric disorders is often seen post surgery. This calls for a comprehensive psychiatric assessment of all patients enrolled for the epilepsy surgery program to be evaluated pre and post surgically to minimize the risk of post surgical psychological disturbances and/or poor quality of life. Efficacious treatment of psychiatric disorders in those having psychiatric morbidity contributes to improved patient wellbeing, seizure freedom and better quality of life. Hence there is a need for most centers globally to include regular psychiatric assessment of epilepsy surgery patients as a protocol.

show abstract

Section: Presurgical and Postsurgical Psychiatric Assessmentmentioning

confidence: 82%

Is psychiatric assessment essential for better epilepsy surgery outcomes?

Sawant

Ravat

Muzumdar

et al. 2016

International Journal of Surgery

View full text Add to dashboard Cite

show abstract

“…A interação entre epilepsia e depressão / ansiedade tem um impacto negativo sobre o controle de crises epilépticas após o tratamento cirúrgico. Um estudo brasileiro avaliou 115 pacientes com epilepsia de lobo temporal submetidos à amigdalohipocampectomia e demonstrou que o TDM pré-cirúrgico foi o mais significante preditor relacionado ao desfecho desfavorável de controle de crises 46 . Tais achados reforçam a existência de uma interação entre processos neurobiológicos deletérios comuns à presença de sintomas psiquiátricos (como os depressivos e de ansiedade) e à geração de crises epilépticas 28 .…”

Section: Complicações Da Associação Entre Epilepsia E Depressão / Ans...unclassified

Avaliação multifatorial de sintomas depressivos, ideação suicida e sintomas de ansiedade em pessoas com epilepsia e cuidadores

Batista João

View full text Add to dashboard Cite

Ao meu Avô e eterno amigo, Benedito João (in memoriam), homem de conduta ilibada e primeiro médico de nossa família.À minha Avó, Maria do Brasil, mulher à frente de seu tempo, pelo incentivo ao aprimoramento contínuo do conhecimento.Aos meus Avós (in memoriam), Nilton Baptista e Olinda Baptista, grandes exemplos de real dedicação ao trabalho e à família. À minha futura esposa, Lais Maya, pelo companheirismo e demonstrações diárias de afeto.Aos meus pais, Sérgio João e Ana João, e ao irmão, André João, pelo apoio incondicional.Aos meus sogros, Nilceana Maya e Ruffo de Freitas Júnior, pela amizade e incentivo à prática científica.

show abstract

Epilepsy surgery in low- and middle-income countries: A scoping review

Watila

Xiao

Keezer

et al. 2019

Epilepsy & Behavior

View full text Add to dashboard Cite

Background: Epilepsy surgery is an important treatment option for people with drug resistant epilepsy. Although surgical procedures are under-utilized worldwide, it is far worse in Low-and Middle-Income Countries (LMIC) and it is less clear to what extent people with drug resistant epilepsy receive such treatment at all. Here we review the existing evidence for the availability and outcome of epilepsy surgery in LMIC, and discuss some challenges and priority. Methods: We used the six stage methodological framework developed by Arskey and O'Malley as a guide. We searched PubMed, Embase, Global Health Archives, Index Medicus for South East Asia Region (IMSEAR), Index Medicus for Eastern Mediterranean Region (IMEMR), Latin American & Caribbean Health Sciences Literature (LILACS), African Journal Online (AJOL), and African Index Medicus (AIM) to identify the relevant literature. Results: We retrieved 148 articles on epilepsy surgery from 31 countries representing 22% of the 143 LMIC. Epilepsy surgery appears established in some of these centers in Asia and Latin America, while some are in their embryonic stage reporting procedures in a small cohort performed mostly by motivated neurosurgeons. The commonest surgical procedure reported was temporal lobectomies. The post-operative seizure-free rates and quality of life are comparable to those in the high-income countries (HIC). Some models have shown that epilepsy surgery can be performed within a resourcelimited setting through collaboration with international partners and through the use of information and communication technology. The cost of surgery is a fraction of what is available in HIC. Conclusion: This review has demonstrated the availability of epilepsy surgery in few LMIC. The information available is inadequate to make any reasonable conclusion of its existence as routine practice. Collaborations with international partners can provide an opportunity to bring high-quality academic training and technological transfer directly to surgeons working in these regions and should be encouraged.

show abstract

Pre-surgical mood disorders associated to worse post-surgical seizure outcome in patients with refractory temporal lobe epilepsy and mesial temporal sclerosis

Cited by 4 publications

References 22 publications

Is psychiatric assessment essential for better epilepsy surgery outcomes?

Is psychiatric assessment essential for better epilepsy surgery outcomes?

Avaliação multifatorial de sintomas depressivos, ideação suicida e sintomas de ansiedade em pessoas com epilepsia e cuidadores

Epilepsy surgery in low- and middle-income countries: A scoping review

Contact Info

Product

Resources

About