Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia

Abstract

Introduction: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. Objective: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose ≥ 100 mg/dl, triglycerides ≥ 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. Method: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. Results: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. Conclusion: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide. (6,7; 2,4-12,5 mg/dl) (5,9; 0,9-33,8 mg/dl para os homens e 4,4; 0,8-30 abstract key words

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

“…The determination of uric and ascorbic acid concentrations in biological fluids such as urine and blood is very important since uric acid is involved in many diseases such as gout [ 149 ], Lesch-Nyhan syndrome [ 150 ] and type two diabetes [ 151 ]. The separations of uric acid from ascorbic acid by voltametric methods with the aid of CNTs have been reported [ 152 , 153 , 154 ].…”

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

“…The determination of uric and ascorbic acid concentrations in biological fluids such as urine and blood is very important since uric acid is involved in many diseases such as gout [148], Lesch-Nyhan syndrome [149] and type two diabetes [150]. The separations of uric acid from ascorbic acid by voltametric methods with the aid of CNTs have been reported [151][152][153].…”