2007
DOI: 10.1590/s1676-24442007000500010
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Primary diffuse large B-cell lymphoma of the oral cavity

Abstract: Lymphomas arising within the oral cavity account for only 3.5% of all oral malignancies. Diffuse large B-cell lymphoma is a non-Hodgkin lymphoma subtype characterized by diffuse proliferation of large neoplastic B lymphoid cells. This paper reports a case of diffuse large B-cell lymphoma affecting the oral cavity of a Brazilian woman, along with its clinical, microscopical, immunohistochemical, and molecular features.

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Cited by 4 publications
(5 citation statements)
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“…[ 6 ] Intraorally it shows maxillary predominance (77%) and the majority of cases are reported on the palate. [ 13 ] This is in accordance with the present case which was also reported in maxillary vestibular region and extended towards the palate.…”
Section: Discussionsupporting
confidence: 94%
“…[ 6 ] Intraorally it shows maxillary predominance (77%) and the majority of cases are reported on the palate. [ 13 ] This is in accordance with the present case which was also reported in maxillary vestibular region and extended towards the palate.…”
Section: Discussionsupporting
confidence: 94%
“…Lip paresthesia and pathologic fractures may also occur, and are common signs of jaw involvement [ 90 ]. Some authors such as Wright et al [ 30 ], Cohen et al [ 32 ], Conteras et al [ 50 ], Farias et al [ 59 ], and Bombeccari et al [ 69 ] made an initial diagnosis of traumatic injury because of the presence of trauma prior to swelling presented at the time of clinical examination. This swelling caused these authors to opt for incisional biopsy in an effort to aid in appropriately beginning the treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Outro ponto importante é o momento do aparecimento da manifestação bucal, que, em sua maioria, ocorre de forma secundária à manifestação inicial. Neste relato de caso encontramos uma manifestação secundária da doença em cavidade oral, que é a forma de apresentação mais comum, diferente do caso descrito por Jham et al, 2 que observaram manifestação bucal primária do linfoma.…”
Section: Relato De Casounclassified
“…O linfoma difuso de grandes células B pode ocorrer fora dos linfonodos, sendo denominados extranodais. 2,3 Na cavidade oral representam cerca de 2% de todos os linfomas não Hodgkin, não apresentam predileção por sexo, acometem em sua maioria pacientes entre a quarta e oitava décadas de vida, com idade média entre 50 e 60 anos. 4 Comumente apresentam-se como tumefações em tecido mole justaósseo no vestíbulo bucal, podendo, em alguns casos, estarem intraósseos com extravasamento para tecido mole, com sintomatologia dolorosa ou parestesia da região.…”
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